Inert gas elimination from lungs with stratified inhomogeneity: theory
P Scheid, MP Hlastala, J Piiper - Respiration Physiology, 1981 - Elsevier
The effects of diffusion limitation in alveolar space (stratified inhomogeneity) on steady state
inert gas elimination by the lung from blood are studied in theory. The lung models used for
the calculations are characterized by a diffusion barrier in the alveolar space, which is
quantified by a diffusive conductance (diffusing capacity), D′. In both homogeneous and
inhomogeneous lung models (with log-normal distribution of V̇ a, Q̇ and D′) increasing
stratified inhomogeneity (decreasing D′) is shown to diminish inerg gas elimination. The …
inert gas elimination by the lung from blood are studied in theory. The lung models used for
the calculations are characterized by a diffusion barrier in the alveolar space, which is
quantified by a diffusive conductance (diffusing capacity), D′. In both homogeneous and
inhomogeneous lung models (with log-normal distribution of V̇ a, Q̇ and D′) increasing
stratified inhomogeneity (decreasing D′) is shown to diminish inerg gas elimination. The …