4rqe

X-ray diffraction
4Å resolution

human Seryl-tRNA synthetase dimer complexed with two molecules of tRNAsec

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-250273 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Serine--tRNA ligase, cytoplasmic Chains: A, C
Molecule details ›
Chains: A, C
Length: 522 amino acids
Theoretical weight: 59.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P49591 (Residues: 1-514; Coverage: 100%)
Gene names: SARS, SARS1, SERS
Sequence domains:
Structure domains:
selenocysteine tRNA Chains: B, D
Molecule details ›
Chains: B, D
Length: 90 nucleotides
Theoretical weight: 28.95 KDa
Source organism: Homo sapiens
Expression system: Not provided
Sequence domains: Selenocysteine transfer RNA

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21
Unit cell:
a: 55.809Å b: 142.023Å c: 115.456Å
α: 90° β: 101.95° γ: 90°
R-values:
R R work R free
0.276 0.274 0.322
Expression systems:
  • Escherichia coli
  • Not provided