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Nociceptor Signalling through ion Channel Regulation via GPCRs.
Int J Mol Sci. 2019 May 20;20(10):2488. doi: 10.3390/ijms20102488.
Int J Mol Sci. 2019.
PMID: 31137507
Free PMC article.
Review.
A triple cysteine motif as major determinant of the modulation of neuronal KV7 channels by the paracetamol metabolite N-acetyl-p-benzo quinone imine.
Ray S, Stampf JL, Kudlacek O, Yang JW, Schicker KW, Graf Y, Losgott T, Boehm S, Salzer I.
Ray S, et al.
Br J Pharmacol. 2024 Aug;181(16):2851-2868. doi: 10.1111/bph.16380. Epub 2024 Apr 24.
Br J Pharmacol. 2024.
PMID: 38657956
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The paracetamol metabolite N-acetylp-benzoquinone imine reduces excitability in first- and second-order neurons of the pain pathway through actions on KV7 channels.
Ray S, Salzer I, Kronschläger MT, Boehm S.
Ray S, et al.
Pain. 2019 Apr;160(4):954-964. doi: 10.1097/j.pain.0000000000001474.
Pain. 2019.
PMID: 30601242
Free PMC article.
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