Epidemiology, Pathogenesis, and Prevention of Head and Neck CancerAndrew F. Olshan Springer Science & Business Media, 2010/03/04 - 207 ページ The purpose of this book is to provide a current perspective on the epidemiology head and neck cancer. Cancers of the oral cavity, pharynx, and larynx comprise an important group of tumors with diverse international patterns of incidence and mortality, established risk factors, suggested association with a virus, and potential genetic susceptibility determinants. These tumors offer a unique insight into mechanisms of cancer initiation and progression and gene-exposure interaction. |
目次
Classification Clinical Features and Molecular Genetic Models | 1 |
US Patterns | 23 |
International Patterns | 40 |
Tobacco and Alcohol | 65 |
Human Papillomavirus and Head and Neck Cancer | 86 |
Dietary Factors | 117 |
Occupation and Other Risk Factors for Head and Neck Cancer | 137 |
Host Susceptibility and Molecular Epidemiology | 155 |
Chemoprevention of Head and Neck Cancers | 187 |
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aerodigestive tract aerodigestive tract cancers alcohol drinking allele alterations Biomarkers Cancer Epidemiol Biomarkers carcinogenesis carcinogenic case-control study cavity and pharynx cervical chemoprevention cigarette Clin Cancer Res clinical cohort study consumption controls disease DNA repair Epidemiol Biomarkers Prev Epidemiology exposure Franceschi frequency genotype head and neck HNSCC HPV-positive human papillomavirus human papillomavirus type hypopharynx IARC incidence rates increased risk Int J Cancer invasive laryngeal cancer leukoplakia males markers molecular mutations Natl Cancer Inst neck cancer neck cancer risk neck squamous cell Olshan oral and pharyngeal oral cancer oral cavity oral cavity cancer Oral Oncol oropharyngeal cancer pharyngeal phenotype pooled analysis population premalignant lesions prevalence prognostic protein regions reported risk factors risk of head risk of laryngeal risk of oral risk of SCCHN risk of squamous role SEER SNPs Spitz squamous cell carcinoma Sturgis survival tobacco and alcohol tobacco smoking trends upper aerodigestive tract variant vegetables viral Wei Q women XRCC1