Abstract
Comparison of the oligonucleotide maps of the RNAs of current human influenza (H1N1) virus isolates shows these strains to be much more closely related to viruses isolated in 1950 than to strains which circulated before or after that period.
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References
Center for Disease Control, Atlanta, Georgia, Morbidity and Mortality Weekly Report 27, 24 (1978).
Center for Disease Control, Atlanta, Georgia, Morbidity and Mortality Weekly Report 27, 16 (1978).
Center for Disease Control, Atlanta, Georgia, Morbidity and Mortality Weekly Report 27, 72 (1978).
Mulder, J. & Masurel, N. Lancet i, 810 (1958).
Tumova, B. & Pereira, H. G. Virology 27, 253 (1965).
Kilbourne, E. D. Science 160, 74 (1968).
Laver, W. G. & Webster, R. G. Virology 48, 445 (1972).
Laver, W. G. & Webster, R. G. Virology 51, 383 (1973).
Robertson, H. D. & Jeppesen, P. G. N. J. molec. Biol. 68, 417 (1972).
Desselberger, U. & Palese, P. Virology (in the press).
Dickson, E., Prensky, W. & Robertson, H. D. Virology 68, 309 (1975).
Gross, H. J., Domdey, H. & Sänger, H. L. Nucleic Acids Res. 4, 2021 (1977).
Wengler, C., Wengler, G. & Filipe, A. R. Virology 78, 124 (1977).
Rommelaere, J., Faller, D. V. & Hopkins, N. Proc. natn. Acad. Sci. U.S.A. 75, 495 (1978).
Clewley, J. P. et al. J. Virol. 23, 152 (1977).
Scholtissek, C., Rohde, W., Harms, E. & Rott, R. Virology 79, 330 (1977).
Palese, P. & Schulmann, J. L. Proc. natn. Acad. Sci. U.S.A. 73, 2142 (1976).
Ritchey, M. B., Palese, P. & Schulman, J. L. J. Virol. 20, 307 (1976).
Frisby, D. Nucleic Acids Res. 4, 2975 (1977).
Donis-Keller, H., Maxam, A. M. & Gilbert, W. Nucleic Acids Res. 4, 2527 (1977).
Desselberger, U. et al. Proc. natn. Acad. Sci. U.S.A. (in the press).
DeWachter, R. & Fiers, W. Analyt. Biochem. 49, 184 (1972).
Billeter, M. A., Parson, J. T. & Coffin, J. M. Proc. natn. Acad. Sci. U.S.A. 71, 3560 (1974).
Bull. WHO 45, 119 (1971).
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Nakajima, K., Desselberger, U. & Palese, P. Recent human influenza A (H1N1) viruses are closely related genetically to strains isolated in 1950. Nature 274, 334–339 (1978). https://doi.org/10.1038/274334a0
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DOI: https://doi.org/10.1038/274334a0
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