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</ref> An [[immunoevasive]] action was the initial normal behavior of the viral protein, in order to avail for the virus to spread to other cells by simply merging them with the infected one. It is believed that the ancestors of modern [[viviparity|viviparous]] mammals evolved after an infection by this virus, enabling the fetus to better resist the immune system of the mother.<ref>{{cite journal|url=http://cvr.bio.uci.edu/downloads/APS.pdf|archive-url=https://web.archive.org/web/20050302153949/http://cvr.bio.uci.edu/downloads/APS.pdf|url-status=dead|archive-date=2005-03-02|title=Can Viruses Make Us Human?|author=Luis P. Villarreal|journal=Proceedings of the American Philosophical Society|volume=148|issue=3|pages=314|date=Sep 2004}}</ref>
Still, the placenta does allow maternal [[IgG antibodies]] to pass to the fetus to protect it against infections. However, these antibodies do not target fetal cells, unless any fetal material has escaped across the placenta where it can come in contact with maternal [[B cell]]s and make those B cells start to produce antibodies against fetal targets. The mother does produce antibodies against foreign [[ABO blood types]], where the fetal blood cells are possible targets, but these preformed antibodies are usually of the [[IgM antibodies|IgM]] type,<ref name=barbreau>[http://www.freshpatents.com/Magnetic-immunodiagnostic-method-for-the-demonstration-of-antibody-antigen-complexes-especially-of-blood-groups-dt20091029ptan20090269776.php Magnetic immunodiagnostic method for the demonstration of antibody/antigen complexes especially of blood groups] {{webarchive|url=https://web.archive.org/web/20120229032947/http://www.freshpatents.com/Magnetic-immunodiagnostic-method-for-the-demonstration-of-antibody-antigen-complexes-especially-of-blood-groups-dt20091029ptan20090269776.php |date=2012-02-29 }} Yves Barbreau, Olivier Boulet, Arnaud Boulet, Alexis Delanoe, Laurence Fauconnier, Fabien Herbert, Jean-Marc Pelosin, Laurent Soufflet. October 2009</ref> and therefore usually do not cross the placenta. Still, rarely, ABO incompatibility can give rise to IgG antibodies that cross the placenta, and are caused by sensitization of mothers (usually of blood type 0) to antigens in foods or bacteria that are homologous to A and B antigens.<ref>[https://www.msdmanuals.com/professional/pediatrics/perinatal-hematologic-disorders/perinatal-anemia MSD manuals > Perinatal Anemia] Last full review/revision Oct 2020</ref>
===Other mechanisms===
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