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Immunology news
Diseases, Conditions, Syndromes
A new drug target identified for diseases associated with leukemia-causing virus
A team of researchers from Penn State College of Medicine found a new target for treating diseases associated with human T-cell leukemia virus type 1 (HTLV-1). They determined that blocking a class of enzymes called kinases, ...
12 hours ago
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Diseases, Conditions, Syndromes
Study reveals 'cell death cascade' in airway cells infected with SARS-CoV-2
Researchers Jenny Ting, Ph.D., the William Kenan Distinguished Professor of Genetics and professor microbiology and immunology at the UNC School of Medicine, and Kaixin Liang, Ph.D., a postdoctoral researcher in the Ting ...
12 hours ago
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Researchers turn the body's B cells into tiny surveillance machines, antibody factories
USC scientists have discovered a way to turn the body's B cells into tiny surveillance machines and antibody factories that can pump out specially designed antibodies to destroy cancer cells or HIV, two of medicine's most ...
18 hours ago
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Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy
The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, ...
19 hours ago
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Kidney transplantation: Combined cell therapy found to reduce donor-specific immune response
A new combined cell therapy for kidney transplants can help to reduce the donor-specific reaction against the transplanted organ without the need for maintenance triple immunosuppression. The overall diversity of the T-cell ...
15 hours ago
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Pig transplant research yields a surprise: Bacon safe for some people allergic to red meat
Some people who develop a weird and terrifying allergy to red meat after a bite from a lone star tick can still eat pork from a surprising source: Genetically modified pigs created for organ transplant research.
Jul 21, 2024
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Research shows spike gene mutations do not correlate with increased SARS-CoV-2 variant severity
New research from UNC Charlotte's Center for Computational Intelligence to Predict Health and Environmental Risks (CIPHER) has found that the two recent and prevalent strains of the virus that cause COVID-19, SARS-CoV-2 variants ...
Jul 19, 2024
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New tech addresses manufacturing bottlenecks for a lifesaving blood cancer treatment
Researchers from the University of South Australia have developed a new technique to significantly enhance a powerful treatment for leukemia and other blood cancers.
Jul 19, 2024
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Eliminating senescent cells could help treat breast, pancreatic cancers
Two studies from Washington University School of Medicine in St. Louis focused on breast cancer and pancreatic cancer suggest that specific types of senescent cells—cells that have stopped dividing and drive inflammation—may ...
Jul 19, 2024
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Tumor-infiltrating lymphocyte therapy marks a milestone in cancer treatment, researchers say
The recent U.S. Food and Drug Administration approval of lifileucel, the first commercial tumor-infiltrating lymphocyte (TIL) therapy for advanced melanoma, marks a significant breakthrough in cancer therapy. In a new commentary ...
Jul 19, 2024
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Study identifies unpredicted immune responses to adenoviral COVID-19 vaccines
Researchers from the University of Liverpool's Center for Drug Safety Science have identified unpredicted T-cell immune responses to the adenoviral (Oxford/AstraZeneca and Janssen) COVID-19 vaccines, but not to the mRNA vaccines.
Jul 18, 2024
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Naturally occurring peptide could serve as a novel protective agent for 'inflammaging'
A naturally occurring peptide called PEPITEM could potentially rejuvenate the immune response in older individuals and protect against "inflammaging," which is widely believed to be the root cause of many age-related diseases.
Jul 18, 2024
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Prenatal Zika infection in mothers found to have long-term immune consequences in children, even without microcephaly
A Cleveland Clinic-led study published in eBioMedicine reveals that maternal Zika virus infections can reprogram fetal immune development, leading to long-term consequences for children's immunity. These changes even occur ...
Jul 18, 2024
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Exploring CAR T-cell therapy for aggressive follicular lymphoma
CAR T-cell therapy is an effective treatment for aggressive subtypes of follicular lymphoma, according to a clinical trial published in Nature Medicine.
Jul 18, 2024
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Scientists pinpoint new drug target for RSV
Scientists have discovered how the dangerous respiratory syncytial virus (RSV) defuses our immune response and, in doing so, have pinpointed an exciting new target for drug developers.
Jul 18, 2024
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Hyaluronic acid lip fillers safe for patients with systemic sclerosis, study finds
Thin lips are not only a common cosmetic concern in patients with scleroderma, a condition that involves tightening and hardening of the skin among other effects on internal organs, but also can impact a person's ability ...
Jul 18, 2024
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Why the most prescribed chemotherapy drug can cause serious heart damage
There's still much to learn about how doxorubicin, a 50-year-old chemotherapy drug, causes its most concerning side effects. While responsible for saving many lives, this treatment sometimes causes cardiac damage that stiffens ...
Jul 17, 2024
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Study shows autoantibodies behind lifelong risk of viral infection
A new study, published in the Journal of Experimental Medicine, shows that about 2% of the population develop autoantibodies against type 1 interferons, mostly later in life. This makes individuals more susceptible to viral ...
Jul 17, 2024
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Immune cells monitor blood platelet maturation in bone marrow, researchers discover
Platelets play an essential role in wound healing. Underproduction can cause devastating bleeding, while overproduction increases the deadly risk of thromboses. Maintaining a constant level of platelets in the blood (homeostasis) ...
Jul 17, 2024
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Patient-driven discovery reveals potential target for autoimmune diseases
A medical mystery served as the genesis for a Yale-led study that has promising implications for treating a range of autoimmune diseases.
Jul 16, 2024
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