Initial validation of a brief provisional diagnostic scale for delirium

Brain Inj. 2010;24(10):1222-30. doi: 10.3109/02699052.2010.498008.

Abstract

Primary objective: The Delirium Diagnostic Tool-Provisional (DDT-Pro) is a newly developed provisional diagnostic tool for delirium presented here. This study evaluated its accuracy and validity in a population of participants with acquired brain injury (ABI).

Research design: Cross-sectional study.

Methods: Thirty-six patients with ABI, including traumatic brain injury (TBI; n = 29) and intraparenchymal haemorrhage (ICH; n = 7) were assessed at admission to inpatient rehabilitation using the DDT-Pro, the Delirium Rating Scale-Revised 98 (DRS-R98) and DSM-IV-TR diagnostic criteria for delirium.

Results: Using receiver operating characteristic (ROC) analysis, the estimate of accuracy, the area under the curve (AUC), was 0.994, and the DDT-Pro accurately classified 35/36 (97%) observations vs the DSM-IV-TR gold standard. The DDT-Pro correlated well with the DRS-R98 both in terms of raw score (r = -0.913, p < 0.0001) and estimates of the duration of delirium (r = 0.975, p < 0.0001).

Conclusions: The DDT-Pro is supported as a measure of delirium following ABI. Further validation in ABI and other medical populations is recommended.

Publication types

  • Evaluation Study
  • Validation Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Area Under Curve
  • Brain Injuries / complications*
  • Brain Injuries / physiopathology
  • Cross-Sectional Studies
  • Delirium / diagnosis*
  • Delirium / physiopathology
  • Female
  • Humans
  • Intracranial Hemorrhages / physiopathology
  • Male
  • Middle Aged
  • Psychiatric Status Rating Scales
  • ROC Curve
  • Sensitivity and Specificity
  • Severity of Illness Index
  • Young Adult