Towards Elucidating the Rotary Mechanism of the Archaellum Machinery

Front Microbiol. 2022 Mar 21:13:848597. doi: 10.3389/fmicb.2022.848597. eCollection 2022.

Abstract

Motile archaea swim by means of a molecular machine called the archaellum. This structure consists of a filament attached to a membrane-embedded motor. The archaellum is found exclusively in members of the archaeal domain, but the core of its motor shares homology with the motor of type IV pili (T4P). Here, we provide an overview of the different components of the archaellum machinery and hypothetical models to explain how rotary motion of the filament is powered by the archaellum motor.

Keywords: archaea; archaella; archaellum motor; cell motility; molecular motors; type IV pili.

Publication types

  • Review