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Ineffability and partition property on $P_{\kappa}\lambda$
1997
Journal of the Mathematical Society of Japan
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Introduction There are several combinatorial properties related with supercompactness. Partition properties and ineffabilities are some of these properties. ...
Normal ultrafilters with the partition property Concerning the partition property of a normal ultrafilter on $\mathcal{P}_{\kappa}\lambda$ , Solovay (see Menas [11] $)$ proved the existence of a normal ...
doi:10.2969/jmsj/04910125
fatcat:zlgw4zrhybas7nhkz7tby24arq
Contributions to the Theory of Large Cardinals through the Method of Forcing
2021
Bulletin of Symbolic Logic
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$\kappa ^+$ and $\kappa ^{++}$ , whenever $\kappa $ is a strong limit singular cardinal witnessing an arbitrary failure of the SCH. ...
Specifically, we aim for a theorem asserting that every $\kappa ^{++}$ -length iteration with support of size $\leq \kappa $ has the $\kappa ^{++}$ -cc, provided the iterates belong to a relevant class ...
Specifically, Part II is devoted to prove the consistency of the Tree Property at both κ + and κ ++ , whenever κ is a strong limit singular cardinal witnessing an arbitrary failure of the SCH. ...
doi:10.1017/bsl.2021.22
fatcat:yynwd7jnyfc2vmkgazoqknnvua
Significant Differences in Physicochemical Properties of Human Immunoglobulin Kappa and Lambda CDR3 Regions
2016
Frontiers in Immunology
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Antibody variable regions are composed of a heavy and a light chain, and in humans, there are two light chain isotypes: kappa and lambda. ...
We also used a published human naïve dataset to investigate the CDR-H3 properties of heavy chains paired with kappa and lambda light chains and probed the Protein Data Bank to investigate the structural ...
(a) Cumulative frequency histograms of CDR-H3 physicochemical properties of kappa and lambda antibodies. Each donor is plotted separately. ...
doi:10.3389/fimmu.2016.00388
pmid:27729912
pmcid:PMC5037968
fatcat:g4k22punjbd53hijlrg6fywju4
FORD DOMAIN OF A CERTAIN HYPERBOLIC 3-MANIFOLD WHOSE BOUNDARY CONSISTS OF A PAIR OF ONCE-PUNCTURED TORI
2007
Intelligence of Low Dimensional Topology 2006
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{i}\mathrm{a}\mathrm{g}(\partial \mathbb{P})$ with the following property. (1) For any $\rho\in\overline{Q\mathcal{F}}$ , the combinatorial structure of $Ph(\rho)$ is described by using $\nu(p)$ . (2) ...
In Section 3, we will see some topological property of such a manifold. ...
doi:10.1142/9789812770967_0001
fatcat:5qdev2dk2jazzp4wq7sstmuv2m
The extent of strength in the club filters
1999
Israel Journal of Mathematics
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We use a number of known combinatorial principles to get that the club filter cannot have these strong properties. ...
{P}_{\kappa}\lambda|s\subseteq a\}\in \mathcal{F}$ . ...
doi:10.1007/bf02785581
fatcat:uhk4ydlx7zbbtnxpxnt4jxzdfa
Antichains in partially ordered sets of singular cofinality
[article]
2006
arXiv
pre-print
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In their paper from 1981, Milner and Sauer conjectured that for any poset P, if cf(P)=lambda>cf(lambda)=kappa, then P must contain an antichain of size kappa. ...
We prove that for lambda>cf(lambda)=kappa, if there exists a cardinal mu<lambda such that cov(lambda,mu,kappa,2)=lambda, then any poset of cofinality lambda contains lambda^kappa antichains of size kappa ...
Assume P, ≤ is a poset. If cf(P, ≤) = λ > cf(λ ) = κ , then P contains an antichain of size κ . ...
arXiv:math/0606021v2
fatcat:qdgrp666infpjjqqsbk7k2dxvq
Affine analogue of the Jack polynomials and the Dunkl operators
2003
Proceedings of the Symposium on Representation Theory
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The set of monomial symmetric functions { $m_{\lambda}= \sum_{\mu\in W\lambda}e^{\mu}$ I A $\in P_{+}$ } form a $\mathbb{C}$ -basis of $\mathbb{C}[P]^{W}$ where $W\lambda$ is the $W$ -orbit of A. ...
}\rangle+i}\kappa)}==$ where $\kappa=\langle\hat{\lambda}, c\rangle+kh^{\vee}$ . 3.3. ...
doi:10.34508/repsympo.2003.0_155
fatcat:7sq4qdmyljfzhgzkul2iywjdly
A database of immunoglobulins with integrated tools: DIGIT
2011
Nucleic Acids Research
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The system allows customized BLAST searches and automatic building of 3D models of the domains to be performed. ...
Other annotations, such as the identification of the complementarity determining regions, assignment of their structural class and identification of mutations with respect to the germline, are computed ...
Immunoglobulin light chains are classified as kappa or lambda according to their serological and sequence properties. ...
doi:10.1093/nar/gkr806
pmid:22080506
pmcid:PMC3245095
fatcat:qfrfy7765vbtxhz3gazthu5plm
Large-scale sequence and structural comparisons of human naive and antigen-experienced antibody repertoires
2016
Proceedings of the National Academy of Sciences of the United States of America
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Specifically, additional information is needed regarding how a history of pathogen and environmental exposure modulates the sequence and conformational properties of naive antibodies to yield a mature ...
structural models across three healthy donors led to a number of key findings: (i) VH and VL gene sequences pair in a combinatorial fashion without detectable pairing restrictions at the population level ...
Kappa CR-paratopes had a median charge of 0, whereas lambda CR-paratopes had a median charge of −1 (P = 1.8 × 10 −9 for naive kappa vs. lambda charge distribution and P < 10 −15 for antigen-experienced ...
doi:10.1073/pnas.1525510113
pmid:27114511
pmcid:PMC4868480
fatcat:prvbapdeynddhmfoghcxb3uig4
Comparison of Combinatorial Signatures of Global Network Dynamics Generated by Two Classes of ODE Models
2019
SIAM Journal on Applied Dynamical Systems
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Recent work has shown that the parameterized dynamics of switching systems can be captured by a combinatorial object, called a Dynamic Signatures Generated by Regulatory Networks (DSGRN) database, that ...
We show that for a given network there is a way to associate the same type of object by considering a continuous time ODE system with a continuous right-hand side, which we call an L-system. ...
k > 0 - 1 if \forall P \in \scrC (\zeta ), \Lambda L k (P )/\gamma k -\varphi k < 0 0 if \exists P, P \prime \in \scrC (\zeta ) such that \Lambda L k (P )/\gamma k -\varphi k > 0 and \Lambda L k (P \prime ...
doi:10.1137/18m1163610
pmid:33679257
pmcid:PMC7932180
fatcat:wajleuivwzh3bkmbayepdx2js4
Transitional B Cells in Early Human B Cell Development – Time to Revisit the Paradigm?
2016
Frontiers in Immunology
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As a result of this an ANOVA analysis of the 236 combinatorial lambda family repertoire showed a significant difference between the immature and the 237 transitional and naïve stages of development (p< ...
kappa (top) and lambda (bottom). ...
doi:10.3389/fimmu.2016.00546
pmid:27994589
pmcid:PMC5133252
fatcat:2wxk4fjzjnh5hohulqmk7ggcgq
IG and TR single chain fragment variable (scFv) sequence analysis: a new advanced functionality of IMGT/V-QUEST and IMGT/HighV-QUEST
2017
BMC Immunology
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of full-length scFv (~850 bp) nucleotide sequences from combinatorial libraries. ...
Giudicelli, P Duroux, S Kossida, M.P. Lefranc To cite this version: V. Giudicelli, P Duroux, S Kossida, M.P. Lefranc. ...
Acknowledgements We thank Gisèle Clofent-Sanchez and Audrey Hemadou for scFv sequences samples and their implication in the development of the project. ...
doi:10.1186/s12865-017-0218-8
pmid:28651553
pmcid:PMC5485737
fatcat:vlkvfytryzh4ricc22dsukuxqe
A Novel Human scFv Library with Non-Combinatorial Synthetic CDR Diversity
2015
PLoS ONE
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To alleviate these issues, we designed and constructed a novel semi-synthetic human scFv library with non-combinatorial, pre-designed CDR diversity and a single native human framework each for heavy, kappa ...
, and lambda chain variable domains. ...
(a) CDR-H2, L1 (kappa and lambda), and L3 (kappa and lambda) contain sequences with varying lengths. ...
doi:10.1371/journal.pone.0141045
pmid:26484868
pmcid:PMC4613135
fatcat:7pgkb7gfnje4dhgujl7z7k2d6m
IMGT standardized criteria for statistical analysis of immunoglobulin V-REGION amino acid properties
2004
Journal of Molecular Recognition
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between kappa and lambda sequences. ...
kappa (IGK) and lambda (IGL) chains were extracted from IMGT/LIGM-DB. ...
for 'IGKV' and 78 for 'IGLV') for the kappa/lambda comparison. ...
doi:10.1002/jmr.647
pmid:14872534
fatcat:xld242p3ung2tj2uq72ksa2wei
On the kappa ring of M_g,n
[article]
2013
arXiv
pre-print
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When g≤ 2 we show that a kappa class κ is trivial if and only if the integral of κ against all boundary strata is trivial. ...
For g=1 we further show that the rank of κ _n-d(M_1,n) is equal to |P_1(d,n-d)|, where P_i(d,k) denotes the set of partitions p=(p_1,...,p_ℓ) of d such that at most k of the numbers p_1,... ...
The second author was partially supported by a grant from Iran's National Elites Foundation. ...
arXiv:1307.2754v2
fatcat:kbduzqfdaveendbvdlnahtx3h4
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