Pharmaceutical polymers and P-glycoprotein: current trends and possible outcomes in drug delivery
Drug resistance is considered a key reason behind the failure of therapeutic medications in
treating chronic diseases, including hypertension, cancer therapeutics, and antimicrobial …
treating chronic diseases, including hypertension, cancer therapeutics, and antimicrobial …
The in vivo pharmacokinetics of block copolymers containing polyethylene glycol used in nanocarrier drug delivery systems
L Yin, Y Pang, L Shan, J Gu - Drug Metabolism and Disposition, 2022 - ASPET
Polyethylene glycol (PEG) is one of the most commonly used synthetic macromolecular
polymers for modifying small molecule drugs, peptides, proteins, or nanodrug delivery …
polymers for modifying small molecule drugs, peptides, proteins, or nanodrug delivery …
Rediscovery of poly (ethylene glycol) s as a cryoprotectant for mesenchymal stem cells
M Patel, JK Park, B Jeong - Biomaterials Research, 2023 - spj.science.org
Background A medium containing dimethyl sulfoxide (DMSO)(10% v/v) is most widely used
for cell cryopreservation at–196° C. However, residual DMSO consistently raises concerns …
for cell cryopreservation at–196° C. However, residual DMSO consistently raises concerns …
Comparative investigation of cellular effects of polyethylene glycol (PEG) derivatives
Nowadays, polyethylene glycols referred to as PEGs are widely used in cosmetics,
consumer care products, and the pharmaceutical industry. Their advantageous properties …
consumer care products, and the pharmaceutical industry. Their advantageous properties …
Ethylene glycol derivative-pendanted quaternary ammonium antibacterial polymers with low cytotoxicity
Cationic poly (quaternary ammonium)(pQA) polymers exhibit excellent antibacterial efficacy
but high cytotoxicity (thus low selectivity), hampering their widespread use as antibacterial …
but high cytotoxicity (thus low selectivity), hampering their widespread use as antibacterial …
[HTML][HTML] Biological fate and interaction with cytochromes P450 of the nanocarrier material, d-α -tocopheryl polyethylene glycol 1000 succinate
T Ren, R Li, L Zhao, JP Fawcett, D Sun, J Gu - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Abstract d-α -Tocopheryl polyethylene glycol 1000 succinate (TPGS, also known as vitamin E-
TPGS) is a biodegradable amphiphilic polymer prepared by esterification of vitamin E with …
TPGS) is a biodegradable amphiphilic polymer prepared by esterification of vitamin E with …
[HTML][HTML] The biological fate of the polymer nanocarrier material monomethoxy poly (ethylene glycol)-block-poly (d, l-lactic acid) in rat
X Meng, Z Zhang, J Tong, H Sun, JP Fawcett… - … Pharmaceutica Sinica B, 2021 - Elsevier
Monomethoxy poly (ethylene glycol)-block-poly (d, l-lactic acid)(PEG-PLA) is a typical
amphiphilic di-block copolymer widely used as a nanoparticle carrier (nanocarrier) in drug …
amphiphilic di-block copolymer widely used as a nanoparticle carrier (nanocarrier) in drug …
Optimized Design of Hyaluronic Acid–Lipid Conjugate Biomaterial for Augmenting CD44 Recognition of Surface-Engineered NK Cells
Triple-negative breast cancer (TNBC) presents treatment challenges due to a lack of
detectable surface receptors. Natural killer (NK) cell-based adaptive immunotherapy is a …
detectable surface receptors. Natural killer (NK) cell-based adaptive immunotherapy is a …
Enhanced cytotoxic activity of pegylated curcumin derivatives: synthesis, structure–activity evaluation, and biological activity
D Lazewski, M Kucinska, E Potapskiy… - International Journal of …, 2023 - mdpi.com
Curcumin has been modified in various ways to broaden its application in medicine and
address its limitations. In this study, we present a series of curcumin-based derivatives …
address its limitations. In this study, we present a series of curcumin-based derivatives …
[HTML][HTML] Influence of PEGylated porous silicon nanoparticles on permeation and efflux of an orally administered antibiotic
Advanced materials-based strategies are proving to be promising in solving the major
problems of oral drug delivery. Herein, Polyethylene glycol (PEG)-functionalized porous …
problems of oral drug delivery. Herein, Polyethylene glycol (PEG)-functionalized porous …