Hutchinson–Gilford progeria syndrome (HGPS) is a rare disease caused by the expression
of progerin, a mutant protein that accelerates aging and precipitates death. Given that …

Background: Progerin, an aberrant protein that accumulates with age, causes the rare
genetic disease Hutchinson-Gilford progeria syndrome (HGPS). Patients who have HGPS …

Cardiovascular disease (CVD) is the main cause of death worldwide, and aging is its
leading risk factor. Aging is much accelerated in Hutchinson–Gilford progeria syndrome …

Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder caused by
progerin, a mutant lamin A variant. HGPS patients display accelerated aging and die …

Background: Hutchinson-Gilford progeria syndrome (HGPS) is a rare disorder characterized
by premature aging and death mainly because of myocardial infarction, stroke, or heart …

Hutchinson–Gilford progeria syndrome (HGPS) is a severe human premature aging disorder
caused by a lamin A mutant named progerin. Death occurs at a mean age of 13 y from …

Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder with features of
accelerated aging. The majority of HGPS cases are caused by a de novo point mutation in …

Hutchinson–Gilford progeria syndrome (HGPS) is a rare premature aging disorder notably
characterized by precocious and deadly atherosclerosis. Almost 90% of HGPS patients carry …

Abstract Aims Hutchinson–Gilford progeria syndrome (HGPS) is a pre-mature aging disorder
caused by the mutation of the LMNA gene leading to an irreversibly farnesylated lamin A …

Hutchinson-Gilford progeria syndrome (HGPS), also known as hereditary progeria
syndrome, is caused by mutations in the LMNA gene and the expression of progerin, which …