Enhancer long-range contacts: The multi-adaptor protein LDB1 is the tie that binds
G Liu, A Dean - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2019 - Elsevier
The eukaryotic genome is organized at varying levels into chromosome territories,
transcriptional compartments and topologically associating domains (TADs), which are …
transcriptional compartments and topologically associating domains (TADs), which are …
[HTML][HTML] Lamina-associated polypeptide (LAP) 2α and nucleoplasmic lamins in adult stem cell regulation and disease
A-type lamins are components of the lamina network at the nuclear envelope, which
mediates nuclear stiffness and anchors chromatin to the nuclear periphery. However, A-type …
mediates nuclear stiffness and anchors chromatin to the nuclear periphery. However, A-type …
Proteins that associate with lamins: many faces, many functions
EC Schirmer, R Foisner - Experimental cell research, 2007 - Elsevier
Lamin-associated polypeptides (LAPs) comprise inner nuclear membrane proteins tightly
associated with the peripheral lamin scaffold as well as proteins forming stable complexes …
associated with the peripheral lamin scaffold as well as proteins forming stable complexes …
Minor loops in major folds: enhancer–promoter looping, chromatin restructuring, and their association with transcriptional regulation and disease
The organization and folding of chromatin within the nucleus can determine the outcome of
gene expression. Recent technological advancements have enabled us to study chromatin …
gene expression. Recent technological advancements have enabled us to study chromatin …
Nuclear lamins—structural proteins with fundamental functions
The nuclear lamina is located between the inner nuclear membrane and the peripheral
chromatin. It is composed of both peripheral and integral membrane proteins, including …
chromatin. It is composed of both peripheral and integral membrane proteins, including …
Retracted: nuclear receptor-enhanced transcription requires motor-and LSD1-dependent gene networking in interchromatin granules
E Nunez, YS Kwon, KR Hutt, Q Hu, MD Cardamone… - Cell, 2008 - cell.com
While the transcriptional machinery has been extensively dissected at the molecular level,
little is known about regulation of chromosomal organization in the three-dimensional space …
little is known about regulation of chromosomal organization in the three-dimensional space …
The nuclear lamina as a gene-silencing hub
YY Shevelyov, DI Nurminsky - Current issues in molecular biology, 2012 - mdpi.com
There is accumulating evidence that the nuclear periphery is a transcriptionally repressive
compartment. A surprisingly large fraction of the genome is either in transient or permanent …
compartment. A surprisingly large fraction of the genome is either in transient or permanent …
[HTML][HTML] Detergent–salt resistance of LAP2α in interphase nuclei and phosphorylation‐dependent association with chromosomes early in nuclear assembly implies …
T Dechat, J Gotzmann, A Stockinger, CA Harris… - The EMBO …, 1998 - embopress.org
Abstract Lamina‐associated polypeptide (LAP) 2 of the inner nuclear membrane (now
LAP2β ) and LAP2α are related proteins produced by alternative splicing, and contain a …
LAP2
Cloning of a cDNA for lamina‐associated polypeptide 2 (LAP2) and identification of regions that specify targeting to the nuclear envelope.
Lamina‐associated polypeptide 2 (LAP2) is an integral membrane protein of the inner
nuclear membrane, which binds directly to both lamin B1 and chromosomes in a mitotic …
nuclear membrane, which binds directly to both lamin B1 and chromosomes in a mitotic …
A cell free system to study reassembly of the nuclear envelope at the end of mitosis
B Burke, L Gerace - Cell, 1986 - cell.com
We describe a cell free system involving total homogenates of metaphase CHO cells, which
yields telophase-like assembly of nuclear envelopes around mitotic chromosomes. During …
yields telophase-like assembly of nuclear envelopes around mitotic chromosomes. During …