Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

BACKGROUND Modern reproductive behavior in most developed countries is characterized
by delayed parenthood. Older gametes are generally less fertile, accumulating and …

In modern post-transition societies, we are reproducing later and living longer. While the
impact of age on female reproductive function has been well studied, much less is known …

Assessments of sperm DNA damage are controversial because of perceived uncertainties
over the relationship with pregnancy and the limited range of therapies available should …

The evolutionary theory of aging supports a trade-off relationship between reproduction and
aging. Aging of the male reproductive system primarily affects the testes, leading to a …

Spermatozoa have the task to deliver an intact paternal genome to the oocyte and to support
a successful embryo development. The high levels of sperm DNA fragmentation (sDF) found …

With the delay of parenthood becoming more common, the age at which men father children
is on the rise. While the effects of advanced maternal age have been well documented, only …

Compared to women, increasing male age is not accompanied by such marked changes in
reproductive function but changes certainly do happen. These include alterations to the …

Delayed family planning and increased parental age increases the risk for infertility and
impaired offspring health. While the impact of ageing on oogenesis is well studied, on …