Atherothrombosis is a complex disease in which cholesterol deposition, inflammation, and
thrombus formation play a major role. Rupture of high-risk, vulnerable plaques is …

The study of atherosclerotic disease during its natural history and after therapeutic
intervention will enhance our understanding of disease progression and regression and aid …

Atherosclerosis and its thrombotic complications are the major cause of morbidity and
mortality in the industrialized countries. Despite advances in our understanding of the …

This second part of the review on atherothrombosis highlights the diffuse nature of the
disease analyzing the feasibility and potential of the noninvasive imaging modalities …

Objectives. Risk of thrombo-embolic stroke is thought to be better reflected by carotid plaque
composition than by luminal stenosis. We set out to determine whether high resolution MRI …

Balloon angioplasty intervention is traumatic to arterial tissue. Fracture mechanisms such as
plaque fissuring and/or dissection occur and constitute major contributions to the lumen …

Vulnerable plaques have thin fibrous caps overlying large necrotic lipid cores. Recent
studies have shown that high-resolution MR imaging can identify these components. We set …

Studying the solid mechanics of angioplasty provides essential insight in the mechanisms of
angioplasty such as overstretching the disease-free tissue, plaque disruption or dissection …

Atherosclerosis is a prevalent disease affecting millions of Americans. Despite our advances
in diagnosis and treatment, atherosclerosis is the leading cause of death in America. High …

volume. 11 However, 2 emerging and most promising techniques—computed tomography
(CT) and MR—are likely to gain wider acceptance by the medical community and to be …