Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
Pathogenicity Factors of Genomic Islands in Intestinal and Extraintestinal Escherichia coli
M Desvaux, G Dalmasso, R Beyrouthy… - Frontiers in …, 2020 - frontiersin.org
Escherichia coli is a versatile bacterial species that includes both harmless commensal
strains and pathogenic strains found in the gastrointestinal tract in humans and warm …
strains and pathogenic strains found in the gastrointestinal tract in humans and warm …
Proksee: in-depth characterization and visualization of bacterial genomes
JR Grant, E Enns, E Marinier, A Mandal… - Nucleic acids …, 2023 - academic.oup.com
Abstract Proksee (https://proksee. ca) provides users with a powerful, easy-to-use, and
feature-rich system for assembling, annotating, analysing, and visualizing bacterial …
feature-rich system for assembling, annotating, analysing, and visualizing bacterial …
Combination of pre-adapted bacteriophage therapy and antibiotics for treatment of fracture-related infection due to pandrug-resistant Klebsiella pneumoniae
A Eskenazi, C Lood, J Wubbolts, M Hites… - Nature …, 2022 - nature.com
A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella
pneumoniae infection after long-term (> 700 days) antibiotic therapy is treated with a pre …
pneumoniae infection after long-term (> 700 days) antibiotic therapy is treated with a pre …
Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosa infection to allow liver transplantation in a toddler
B Van Nieuwenhuyse, D Van der Linden… - Nature …, 2022 - nature.com
Post-operative bacterial infections are a leading cause of mortality and morbidity after
ongoing liver transplantation. Bacteria causing these infections in the hospital setting can …
ongoing liver transplantation. Bacteria causing these infections in the hospital setting can …
Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome
Mobile genetic elements (MGEs) carrying antibiotic resistance genes (ARGs) disseminate
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene …
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene …
Nitrogen cycling and microbial cooperation in the terrestrial subsurface
The nitrogen cycle plays a major role in aquatic nitrogen transformations, including in the
terrestrial subsurface. However, the variety of transformations remains understudied. To …
terrestrial subsurface. However, the variety of transformations remains understudied. To …
CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database
Abstract The Comprehensive Antibiotic Resistance Database (CARD; card. mcmaster. ca)
combines the Antibiotic Resistance Ontology (ARO) with curated AMR gene (ARG) …
combines the Antibiotic Resistance Ontology (ARO) with curated AMR gene (ARG) …
VRprofile2: detection of antibiotic resistance-associated mobilome in bacterial pathogens
M Wang, YX Goh, C Tai, H Wang, Z Deng… - Nucleic acids …, 2022 - academic.oup.com
VRprofile2 is an updated pipeline that rapidly identifies diverse mobile genetic elements in
bacterial genome sequences. Compared with the previous version, three major …
bacterial genome sequences. Compared with the previous version, three major …
[PDF][PDF] A bioinformatic analysis of integrative mobile genetic elements highlights their role in bacterial adaptation
Mobile genetic elements (MGEs) contribute to bacterial adaptation and evolution; however,
high-throughput, unbiased MGE detection remains challenging. We describe MGEfinder, a …
high-throughput, unbiased MGE detection remains challenging. We describe MGEfinder, a …