Antimicrobial resistance monitoring of water environments: a framework for standardized methods and quality control

K Liguori, I Keenum, BC Davis, J Calarco… - … science & technology, 2022 - ACS Publications
Antimicrobial resistance (AMR) is a grand societal challenge with important dimensions in
the water environment that contribute to its evolution and spread. Environmental monitoring …

Surveillance of antimicrobial resistance in low-and middle-income countries: a scattered picture

K Iskandar, L Molinier, S Hallit, M Sartelli… - … Resistance & Infection …, 2021 - Springer
Data on comprehensive population-based surveillance of antimicrobial resistance is lacking.
In low-and middle-income countries, the challenges are high due to weak laboratory …

Environmental factors shaping the gut microbiome in a Dutch population

R Gacesa, A Kurilshikov, A Vich Vila, T Sinha… - Nature, 2022 - nature.com
The gut microbiome is associated with diverse diseases,–, but a universal signature of a
healthy or unhealthy microbiome has not been identified, and there is a need to understand …

Assessment of global health risk of antibiotic resistance genes

Z Zhang, Q Zhang, T Wang, N Xu, T Lu, W Hong… - Nature …, 2022 - nature.com
Antibiotic resistance genes (ARGs) have accelerated microbial threats to human health in
the last decade. Many genes can confer resistance, but evaluating the relative health risks of …

The PATRIC Bioinformatics Resource Center: expanding data and analysis capabilities

JJ Davis, AR Wattam, RK Aziz, T Brettin… - Nucleic acids …, 2020 - academic.oup.com
Abstract The PathoSystems Resource Integration Center (PATRIC) is the bacterial
Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious …

CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database

BP Alcock, AR Raphenya, TTY Lau… - Nucleic acids …, 2020 - academic.oup.com
Abstract The Comprehensive Antibiotic Resistance Database (CARD; https://card. mcmaster.
ca) is a curated resource providing reference DNA and protein sequences, detection models …

Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth

Y Shao, SC Forster, E Tsaliki, K Vervier, A Strang… - Nature, 2019 - nature.com
Immediately after birth, newborn babies experience rapid colonization by microorganisms
from their mothers and the surrounding environment. Diseases in childhood and later in life …

Validating the AMRFinder tool and resistance gene database by using antimicrobial resistance genotype-phenotype correlations in a collection of isolates

M Feldgarden, V Brover, DH Haft… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Antimicrobial resistance (AMR) is a major public health problem that requires publicly
available tools for rapid analysis. To identify AMR genes in whole-genome sequences, the …

A catalogue of 1,167 genomes from the human gut archaeome

CM Chibani, A Mahnert, G Borrel, A Almeida… - Nature …, 2022 - nature.com
The human gut microbiome plays an important role in health, but its archaeal diversity
remains largely unexplored. In the present study, we report the analysis of 1,167 …

Towards the biogeography of prokaryotic genes

LP Coelho, R Alves, ÁR Del Río, PN Myers… - Nature, 2022 - nature.com
Microbial genes encode the majority of the functional repertoire of life on earth. However,
despite increasing efforts in metagenomic sequencing of various habitats,–, little is known …