Mutations of Lamin A/C gene (LMNA) cause laminopathies, a group of disorders associated
with a wide spectrum of clinically distinct phenotypes, affecting different tissues and organs …

Mutations in the gene for lamin A/C (LMNA) cause a diverse range of diseases known as
laminopathies. LMNA-related cardiomyopathy is a common inherited heart disease and is …

Cardiac laminopathies, associated with mutations in the LMNA gene, encompass a wide
spectrum of clinical manifestations, involving electrical and mechanical alterations of …

Lamins A and C are intermediate filament nuclear envelope proteins encoded by the LMNA
gene. Mutations in LMNA cause autosomal dominant severe heart disease, accounting for …

The nuclear lamina is a critical structural domain for the maintenance of genomic stability
and whole-cell mechanics. Mutations in the LMNA gene, which encodes nuclear A-type …

The cardiac phenotype associated to LMNA mutations is now much clearer, but the
molecular mechanisms underlying cellular and tissue specific phenotypes are still puzzling …

Mutations in the LMNA gene, which encodes A-type nuclear lamins (intermediate filament
proteins expressed in most differentiated somatic cells), cause a diverse range of diseases …

Mutations in the lamin A/C (LMNA) gene, which encodes nuclear membrane proteins, cause
a variety of human conditions including dilated cardiomyopathy (DCM) with associated …

Mutation in the LMNA gene, encoding lamin A/C, causes a diverse group of diseases called
laminopathies. Cardiac involvement is the major cause of death and manifests as dilated …

Mutations in the lamin A/C gene (LMNA) were associated with dilated cardiomyopathy
(DCM) and, recently, were related to severe forms of arrhythmogenic right ventricular …