Targeting mesenchymal stromal cells/pericytes (MSCs) with pulsed electromagnetic field (PEMF) has the potential to treat rheumatoid arthritis

CL Ross, DC Ang, G Almeida-Porada - Frontiers in immunology, 2019 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic
inflammation of synovium (synovitis), with inflammatory/immune cells and resident fibroblast …

The use of pulsed electromagnetic field to modulate inflammation and improve tissue regeneration: a review

CL Ross, Y Zhou, CE McCall, S Soker, TL Criswell - Bioelectricity, 2019 - liebertpub.com
Pulsed electromagnetic field (PEMF) is emerging as innovative treatment for regulation of
inflammation, which could have significant effects on tissue regeneration. PEMF modulates …

Pulsed electromagnetic fields potentiate the paracrine function of mesenchymal stem cells for cartilage regeneration

D Parate, ND Kadir, C Celik, EH Lee, JHP Hui… - Stem cell research & …, 2020 - Springer
Background The mesenchymal stem cell (MSC) secretome, via the combined actions of its
plethora of biologically active factors, is capable of orchestrating the regenerative responses …

Magnetic enhancement of chondrogenic differentiation of mesenchymal stem cells

J Huang, Y Liang, Z Huang, P Zhao… - ACS biomaterials …, 2019 - ACS Publications
Pulsed electromagnetic field therapy, or pulsed signal therapy, has shown efficacy in
treating many illnesses, including knee osteoarthritis. Although the mechanism is not fully …

Pulsed electromagnetic field attenuates osteoarthritis progression in a murine destabilization-induced model through inhibition of TNF-αあるふぁ and IL-6 signaling

X Yang, H Guo, W Ye, L Yang, C He - Cartilage, 2021 - journals.sagepub.com
Objective To investigate the anti-inflammatory effects and mechanisms of pulsed
electromagnetic field (PEMF) in the treatment of osteoarthritis (OA) in the destabilization of …

[HTML][HTML] Effects of electromagnetic fields on osteoarthritis

T Wang, W Xie, W Ye, C He - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Osteoarthritis (OA), characterized by joint malfunction and chronic disability, is the most
common form of arthritis. The pathogenesis of OA is unclear, yet studies have shown that it is …

Pulsed electromagnetic field (PEMF) treatment ameliorates murine model of collagen-induced arthritis

JE Hong, CG Lee, S Hwang, J Kim, M Jo… - International journal of …, 2023 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease of the joint synovial membranes. RA is
difficult to prevent or treat; however, blocking proinflammatory cytokines is a general …

Pulsed electromagnetic field stimulation in osteogenesis and chondrogenesis: signaling pathways and therapeutic implications

K Varani, F Vincenzi, S Pasquini, I Blo, S Salati… - International Journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) are the main cell players in tissue repair and thanks to their
self-renewal and multi-lineage differentiation capabilities, they gained significant attention …

The Effect of Different Frequencies of Pulsed Electromagnetic Fields on Cartilage Repair of Adipose Mesenchymal Stem Cell–Derived Exosomes in Osteoarthritis

Y Xu, Q Wang, XX Wang, XN Xiang, JL Peng… - Cartilage, 2022 - journals.sagepub.com
Background The intra-articular injection of mesenchymal stem cell (MSC)-derived exosomes
has already been proved to reverse osteoarthritic cartilage degeneration. Pulsed …

Role of pulsed electromagnetic fields (PEMF) on tenocytes and myoblasts—potential application for treating rotator cuff tears

M Liu, C Lee, D Laron, N Zhang… - Journal of …, 2017 - Wiley Online Library
The post‐surgery integrity of the tendons and muscle quality are the two major factors in
success of rotator cuff (RC) repair. Though surgical techniques for rotator cuff repair have …