B cell regulation in cancer and anti-tumor immunity
A Sarvaria, JA Madrigal, A Saudemont - Cellular & molecular …, 2017 - nature.com
The balance between immune effector cells and immunosuppressive cells and how this
regulates the tumor microenvironment has been well described. A significant contribution of …
regulates the tumor microenvironment has been well described. A significant contribution of …
Human regulatory B cells in health and disease: therapeutic potential
C Mauri, M Menon - The Journal of clinical investigation, 2017 - Am Soc Clin Investig
Regulatory B cells (Bregs) modulate immune responses predominantly, although not
exclusively, via the release of IL-10. The importance of human Bregs in the maintenance of …
exclusively, via the release of IL-10. The importance of human Bregs in the maintenance of …
Pathogenesis of immune thrombocytopenia
S Audia, M Mahévas, M Samson, B Godeau… - Autoimmunity …, 2017 - Elsevier
Immune thrombocytopenia (ITP) is a rare autoimmune disease due to an abnormal T cell
response, notably supported by splenic T follicular helper cells, that stimulates the …
response, notably supported by splenic T follicular helper cells, that stimulates the …
Skin immune landscape: inside and outside the organism
F Abdallah, L Mijouin, C Pichon - Mediators of inflammation, 2017 - Wiley Online Library
The skin is an essential organ to the human body protecting it from external aggressions and
pathogens. Over the years, the skin was proven to have a crucial immunological role, not …
pathogens. Over the years, the skin was proven to have a crucial immunological role, not …
[HTML][HTML] Regulatory B cells: phenotype, function and role in transplantation
CM Wortel, S Heidt - Transplant immunology, 2017 - Elsevier
While B cells are traditionally known for their roles in antibody production, antigen
presentation and cytokine production, recent studies have highlighted the existence of B …
presentation and cytokine production, recent studies have highlighted the existence of B …
Arthritis models: usefulness and interpretation
Animal models of arthritis are used to better understand pathophysiology of a disease or to
seek potential therapeutic targets or strategies. Focusing on models currently used for …
seek potential therapeutic targets or strategies. Focusing on models currently used for …
Effector and regulatory B cells in multiple sclerosis
E Staun-Ram, A Miller - Clinical immunology, 2017 - Elsevier
The role of B cells in the pathogenesis of Multiple Sclerosis (MS), an autoimmune
neurodegenerative disease, is becoming eminent in recent years, but the specific …
neurodegenerative disease, is becoming eminent in recent years, but the specific …
IL-10 producing Bregs are impaired in psoriatic arthritis and psoriasis and inversely correlate with IL-17-and IFNγ -producing T cells
Our aim was to study CD19 (+) CD27 (+) CD24 (high) memory and CD19 (+) CD24 (high)
CD38 (high) transitional and IL-10+ Breg cells, known to inhibit Th1 and Th17 cells in …
CD38 (high) transitional and IL-10+ Breg cells, known to inhibit Th1 and Th17 cells in …
Regulatory B cells in pregnancy: lessons from autoimmunity, graft tolerance, and cancer
RM Guzman-Genuino, KR Diener - Frontiers in immunology, 2017 - frontiersin.org
The success of pregnancy is contingent on the maternal immune system recognizing and
accommodating a growing semi-allogeneic fetus. Specialized subsets of lymphocytes …
accommodating a growing semi-allogeneic fetus. Specialized subsets of lymphocytes …
Advances in the pathophysiology of primary immune thrombocytopenia
M Perera, T Garrido - Hematology, 2017 - Taylor & Francis
Objectives: Classically, immune thrombocytopenia (ITP) was thought to be caused by the
destruction and insufficient production of platelets, as mediated by autoantibodies. More …
destruction and insufficient production of platelets, as mediated by autoantibodies. More …