Strategies to improve the efficiency of somatic cell nuclear transfer

K Srirattana, M Kaneda, R Parnpai - International Journal of Molecular …, 2022 - mdpi.com
Mammalian oocytes can reprogram differentiated somatic cells into a totipotent state through
somatic cell nuclear transfer (SCNT), which is known as cloning. Although many mammalian …

Use of bisection to reduce mitochondrial DNA in the bovine oocyte

L Adams, Y Liu, B Durrant, E Ruggeri, C Young… - JoVE (Journal of …, 2022 - jove.com
Interspecies somatic cell nuclear transfer (iSCNT) may be used to rescue endangered
species, but two distinct populations of mitochondrial DNA (mtDNA) exist within the …