Fever may be the only clinical symptom at the onset of infection in neutropenic cancer
patients undergoing myelosuppressive chemotherapy. A prompt and evidence-based …

Hematopoietic stem cell transplantation (HSCT)(also known as ''bone marrow
transplantation'') is associated with a variety of infectious complications that pose serious …

This document updates and expands the initial Infectious Diseases Society of America
(IDSA) Fever and Neutropenia Guideline that was published in 1997 and first updated in …

Neutropenic colitis is a severe condition usually affecting immunocompromised patients. Its
exact pathogenesis is not completely understood. The main elements in disease onset …

Neutropenic enterocolitis (NEC) is a life-threatening disease with substantial morbidity and
mortality, seen primarily in patients with hematologic malignancies. The frequency of NEC …

Objective Bleeding ulcers and erosions are hallmarks of active ulcerative colitis (UC).
However, the mechanisms controlling bleeding and mucosal haemostasis remain elusive …

Posaconazole oral suspension, a marketed extended-spectrum triazole with proven efficacy
as antifungal treatment and prophylaxis, should be taken with food to maximize absorption …

Opinion statement Neutropenic enterocolitis is a life-threatening gastrointestinal (GI)
complication of chemotherapy most often associated with leukemia or lymphoma. Early …

Polymicrobial infections account for∼ 15% of infections in immunocompromised patients
with cancer. However, limited information exists regarding the spectrum and microbiology of …

We previously demonstrated vast expansion of hypoxic areas in the leukemic
microenvironment and provided a rationale for using hypoxia-activated prodrugs. PR104 is …