Bionanoparticles in cancer imaging, diagnosis, and treatment

Y Li, Q Bao, S Yang, M Yang, C Mao - View, 2022 - Wiley Online Library
Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …

Rationally designed molecular beacons for bioanalytical and biomedical applications

J Zheng, R Yang, M Shi, C Wu, X Fang, Y Li… - Chemical Society …, 2015 - pubs.rsc.org
Nucleic acids hold promise as biomolecules for future applications in biomedicine and
biotechnology. Their well-defined structures and compositions afford unique chemical …

Nucleic acid based molecular devices

Y Krishnan, FC Simmel - Angewandte Chemie International …, 2011 - Wiley Online Library
In biology, nucleic acids are carriers of molecular information: DNA's base sequence stores
and imparts genetic instructions, while RNA's sequence plays the role of a messenger and a …

Dramatic Rise in Plasma Viremia after CD8+ T Cell Depletion in Simian Immunodeficiency Virus–infected Macaques

X Jin, DE Bauer, SE Tuttleton, S Lewin… - The Journal of …, 1999 - rupress.org
To determine the role of CD8+ T cells in controlling simian immunodeficiency virus (SIV)
replication in vivo, we examined the effect of depleting this cell population using an anti-CD8 …

Multicolor molecular beacons for allele discrimination

S Tyagi, DP Bratu, FR Kramer - Nature biotechnology, 1998 - nature.com
Molecular beacons are hairpin-shaped oligonucleotide probes that report the presence of
specific nucleic acids in homogenous solutions. When they bind to their targets they …

Electrochemical interrogation of conformational changes as a reagentless method for the sequence-specific detection of DNA

C Fan, KW Plaxco, AJ Heeger - Proceedings of the …, 2003 - National Acad Sciences
We report a strategy for the reagentless transduction of DNA hybridization into a readily
detectable electrochemical signal by means of a conformational change analogous to the …

Molecular engineering of DNA: molecular beacons

K Wang, Z Tang, CJ Yang, Y Kim… - Angewandte Chemie …, 2009 - Wiley Online Library
Molecular beacons (MBs) are specifically designed DNA hairpin structures that are widely
used as fluorescent probes. Applications of MBs range from genetic screening, biosensor …

DNA probes using fluorescence resonance energy transfer (FRET): designs and applications

VV Didenko - Biotechniques, 2001 - Taylor & Francis
Fluorescence resonance energy transfer (FRET) is widely used in biomedical research as a
reporter method. Oligonucleotides with a DNA backbone and one or several chromophore …

SNPs in forensic genetics: a review on SNP typing methodologies

B Sobrino, M Brión, A Carracedo - Forensic science international, 2005 - Elsevier
There is an increasing interest in single nucleotide polymorphism (SNP) typing in the
forensic field, not only for the usefulness of SNPs for defining Y chromosome or mtDNA …

Real‐time polymerase chain reaction

J Wilhelm, A Pingoud - Chembiochem, 2003 - Wiley Online Library
Real‐time PCR is the state‐of‐the‐art technique to quantify nucleic acids for mutation
detection, genotyping and chimerism analysis. Since its development in the 1990s, many …