Bionanoparticles in cancer imaging, diagnosis, and treatment
Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …
Rationally designed molecular beacons for bioanalytical and biomedical applications
J Zheng, R Yang, M Shi, C Wu, X Fang, Y Li… - Chemical Society …, 2015 - pubs.rsc.org
Nucleic acids hold promise as biomolecules for future applications in biomedicine and
biotechnology. Their well-defined structures and compositions afford unique chemical …
biotechnology. Their well-defined structures and compositions afford unique chemical …
Nucleic acid based molecular devices
Y Krishnan, FC Simmel - Angewandte Chemie International …, 2011 - Wiley Online Library
In biology, nucleic acids are carriers of molecular information: DNA's base sequence stores
and imparts genetic instructions, while RNA's sequence plays the role of a messenger and a …
and imparts genetic instructions, while RNA's sequence plays the role of a messenger and a …
Dramatic Rise in Plasma Viremia after CD8+ T Cell Depletion in Simian Immunodeficiency Virus–infected Macaques
X Jin, DE Bauer, SE Tuttleton, S Lewin… - The Journal of …, 1999 - rupress.org
To determine the role of CD8+ T cells in controlling simian immunodeficiency virus (SIV)
replication in vivo, we examined the effect of depleting this cell population using an anti-CD8 …
replication in vivo, we examined the effect of depleting this cell population using an anti-CD8 …
Multicolor molecular beacons for allele discrimination
Molecular beacons are hairpin-shaped oligonucleotide probes that report the presence of
specific nucleic acids in homogenous solutions. When they bind to their targets they …
specific nucleic acids in homogenous solutions. When they bind to their targets they …
Electrochemical interrogation of conformational changes as a reagentless method for the sequence-specific detection of DNA
We report a strategy for the reagentless transduction of DNA hybridization into a readily
detectable electrochemical signal by means of a conformational change analogous to the …
detectable electrochemical signal by means of a conformational change analogous to the …
Molecular engineering of DNA: molecular beacons
Molecular beacons (MBs) are specifically designed DNA hairpin structures that are widely
used as fluorescent probes. Applications of MBs range from genetic screening, biosensor …
used as fluorescent probes. Applications of MBs range from genetic screening, biosensor …
DNA probes using fluorescence resonance energy transfer (FRET): designs and applications
VV Didenko - Biotechniques, 2001 - Taylor & Francis
Fluorescence resonance energy transfer (FRET) is widely used in biomedical research as a
reporter method. Oligonucleotides with a DNA backbone and one or several chromophore …
reporter method. Oligonucleotides with a DNA backbone and one or several chromophore …
SNPs in forensic genetics: a review on SNP typing methodologies
B Sobrino, M Brión, A Carracedo - Forensic science international, 2005 - Elsevier
There is an increasing interest in single nucleotide polymorphism (SNP) typing in the
forensic field, not only for the usefulness of SNPs for defining Y chromosome or mtDNA …
forensic field, not only for the usefulness of SNPs for defining Y chromosome or mtDNA …
Real‐time polymerase chain reaction
J Wilhelm, A Pingoud - Chembiochem, 2003 - Wiley Online Library
Real‐time PCR is the state‐of‐the‐art technique to quantify nucleic acids for mutation
detection, genotyping and chimerism analysis. Since its development in the 1990s, many …
detection, genotyping and chimerism analysis. Since its development in the 1990s, many …