Networking brainstem and basal ganglia circuits for movement

S Arber, RM Costa - Nature Reviews Neuroscience, 2022 - nature.com
The execution and learning of diverse movements involve neuronal networks distributed
throughout the nervous system. The brainstem and basal ganglia are key for processing …

[HTML][HTML] Cortico-spinal modularity in the parieto-frontal system: A new perspective on action control

RJ Bufacchi, A Battaglia-Mayer, GD Iannetti… - Progress in …, 2023 - Elsevier
Classical neurophysiology suggests that the motor cortex (MI) has a unique role in action
control. In contrast, this review presents evidence for multiple parieto-frontal spinal …

Dopamine transients follow a striatal gradient of reward time horizons

A Mohebi, W Wei, L Pelattini, K Kim, JD Berke - Nature Neuroscience, 2024 - nature.com
Animals make predictions to guide their behavior and update those predictions through
experience. Transient increases in dopamine (DA) are thought to be critical signals for …

Distinct roles for motor cortical and thalamic inputs to striatum during motor skill learning and execution

SBE Wolff, R Ko, BP Ölveczky - Science advances, 2022 - science.org
The acquisition and execution of motor skills are mediated by a distributed motor network,
spanning cortical and subcortical brain areas. The sensorimotor striatum is an important cog …

[HTML][HTML] Continuous whole-body 3D kinematic recordings across the rodent behavioral repertoire

JD Marshall, DE Aldarondo, TW Dunn, WL Wang… - Neuron, 2021 - cell.com
In mammalian animal models, high-resolution kinematic tracking is restricted to brief
sessions in constrained environments, limiting our ability to probe naturalistic behaviors and …

Tracking neural activity from the same cells during the entire adult life of mice

S Zhao, X Tang, W Tian, S Partarrieu, R Liu… - Nature …, 2023 - nature.com
Stably recording the electrical activity of the same neurons over the adult life of an animal is
important to neuroscience research and biomedical applications. Current implantable …

Principles of gait encoding in the subthalamic nucleus of people with Parkinson's disease

Y Thenaisie, K Lee, C Moerman, S Scafa… - Science translational …, 2022 - science.org
Disruption of subthalamic nucleus dynamics in Parkinson's disease leads to impairments
during walking. Here, we aimed to uncover the principles through which the subthalamic …

Purkinje cell microzones mediate distinct kinematics of a single movement

FGC Blot, JJ White, A van Hattem, L Scotti… - nature …, 2023 - nature.com
The classification of neuronal subpopulations has significantly advanced, yet its relevance
for behavior remains unclear. The highly organized flocculus of the cerebellum, known to …

Dissociating the contributions of sensorimotor striatum to automatic and visually guided motor sequences

KGC Mizes, J Lindsey, GS Escola, BP Ölveczky - Nature Neuroscience, 2023 - nature.com
The ability to sequence movements in response to new task demands enables rich and
adaptive behavior. However, such flexibility is computationally costly and can result in …

Opposing roles of the dorsolateral and dorsomedial striatum in the acquisition of skilled action sequencing in rats

KM Turner, A Svegborn, M Langguth… - Journal of …, 2022 - Soc Neuroscience
The shift in control from dorsomedial to dorsolateral striatum during skill and habit formation
has been well established, but whether striatal subregions orchestrate this shift …