The aim of this review was to examine the evidence for age-related changes of the
hypothalamic-pituitary-adrenal (HPA) axis in both physiological and pathological aging, on the basis …

The increased generation of reactive oxygen species that occurs in the condition of obesity
may be responsible for oxidative injury to erythrocyte membranes, which could lead to a …

The simultaneous evaluation of the circadian rhythm of plasma melatonin and ACTH and of
serum cortisol and DHEAS represents a clinically reliable tool to appreciate the …

Melatonin secretion is an endogenous synchronizer, and it may possess some anti‐aging
properties. Thus we examined melatonin levels in physiological aging, in extreme senescence …

Hippocampus plays a crucial role in learning and memory and, in spite of its remarkable
plasticity, it is also particularly sensitive to stress hormones due to its high concentration of …

We studied the circadian rhythm of plasma melatonin, growth hormone (GH), prolactin (PRL),
adrenocorticotropic hormone (ACTH), and Cortisol in 52 mentally healthy old subjects, 35 …

The biosynthetic dissociation of the adrenocortical secretion occurring with age may have a
pathogenetic role in the pathophysiology of brain aging. We studied cortisol and DHEAS …

The pineal and pituitary–adrenocortical secretions play an important role in adaptive responses
of the organism acting as coordinating signals for both several biological rhythms and …

Purpose. To analyse images obtained by indocyanine green angiography in central serous
chorioretinopathy (CSC). Methods. Ninety patients affected with CSC were examined using …

Abstract Changes in thyroid function are often described in elderly subjects; however, their
pathophysiologic significance and the possible contributory role of both malnutrition and …