Abstract The SAGE (Standards-Based Active Guideline Environment) project was formed to
create a methodology and infrastructure required to demonstrate integration of decision …

The success of clinical decision-support systems requires that they are seamlessly
integrated into clinical workflow. In the SAGE project, which aims to create the technological …

Objective: A gap exists between the information contained in published clinical practice
guidelines and the knowledge and information that are necessary to implement them. This …

This paper describes and discusses a framework that facilitates the development of clinical
guideline application tasks. The framework, named GASTON covers all stages in the …

We report the first successful test of an interoperable guideline execution engine that
interprets encoded clinical guideline content and executes that content via functions of a …

Representation of clinical practice guidelines in a computer-interpretable format is a critical
issue for guideline development, implementation, and evaluation. We studied 11 types of …

Compared to guideline representation formalisms, data and knowledge modeling for clinical
guidelines is a relatively neglected area. Yet it has enormous impact on the format and …

Objective: To develop a knowledge representation model for clinical practice guidelines that
is linguistically adequate, comprehensible, reusable, and maintainable. Design: Decision …

Objective: To allow exchange of clinical practice guidelines among institutions and computer-
based applications. Design: The GuideLine Interchange Format (GLIF) specification consists …

A number of barriers exist which prevent the widespread integration of practice guidelines
with electronic medical record systems. These include dependencies on clinical databases …