Iron supplementation in pregnancy or infancy and motor development: a randomized controlled trial

RM Angulo-Barroso, M Li, DCC Santos, Y Bian… - …, 2016 - publications.aap.org
METHODS: The study was a randomized controlled trial (RCT) of infancy iron
supplementation linked to an RCT of pregnancy iron supplementation, conducted in Hebei,
China. A total of 1482 infants were randomly assigned to receive placebo (n= 730) or
supplemental iron (n= 752) from 6 weeks to 9 months. Gross motor development (assessed
by using the Peabody Developmental Motor Scale, Second Edition, instrument) was the
primary outcome. Neurologic integrity and motor quality were secondary outcomes …