A serial longitudinal quantitative MRI study of cerebral changes in first-episode schizophrenia using image segmentation and subvoxel registration
BK Puri, SB Hutton, N Saeed, A Oatridge… - Psychiatry Research …, 2001 - Elsevier
Lateral ventricular enlargement is the most consistently replicated brain abnormality found in
schizophrenia. This article reports a first episode, longitudinal study of ventricular volume
using high-resolution serial magnetic resonance imaging (MRI) and recently developed
techniques for image registration and quantitation. Baseline and follow-up (on average 8
months later) MRI scans were carried out on 24 patients and 12 controls. Accurate subvoxel
registration was performed and subtraction images were produced to reveal areas of …
schizophrenia. This article reports a first episode, longitudinal study of ventricular volume
using high-resolution serial magnetic resonance imaging (MRI) and recently developed
techniques for image registration and quantitation. Baseline and follow-up (on average 8
months later) MRI scans were carried out on 24 patients and 12 controls. Accurate subvoxel
registration was performed and subtraction images were produced to reveal areas of …