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CluSTr
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CluSTr DATABASE
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 CluSTr   

The CluSTr database offers an automatic classification of UniProt Knowledgebase proteins into groups of related proteins. The clustering is based on analysis of all pairwise comparisons between protein sequences. The database provides links to InterPro, which integrates information on protein families, domains and functional sites from PROSITEPRINTSPfamProDomSMARTTIGRFAMs PDB, SUPERFAMILY and  PIR Superfamily.

  About CluSTr
CluSTr is a database containing information about proteins from 195 organisms with completely sequenced genomes.

A hierarchy of clusters of related proteins (ordered by their degree of similarity) is available for the full data set. Additionally, hierarchies for the proteins of each individual species (and certain collections of species) are available.

Proteomes represented in CluSTr include 11 complete eukaryote proteomes (Arabidopsis thaliana, Caenorhabditis elegans, Drosophila melanogaster, Encephalitozoon cuniculi, Guillardia theta, Homo sapiens, Mus musculus, Saccharomyces cerevisiae, Schizosaccharomyces pombe and Rattus norvegicus (Rat)).
Analysis of all complete proteomes can be found in Integr8.

Further information about the database methodology, the database schema and available data can be found in the Documentation page.

The CluSTr project is funded by the European Commission as the TEMBLOR, contract-no. QLRI-CT-2001-00015 under the RTD programme "Quality of Life and Management of Living Resources".

The bulk of protein similarity data in CluSTr has been produced at SARA supercomputer centre (Amsterdam, The Netherlands) under the Protein World project, which involved collaboration between EBI and Gene-IT (Paris, France), Organon (Oss, The Netherlands) and the Netherlands Bioinformatics Centre (NBIC)/BioASP. The Protein World project has been funded so far by Organon and the Dutch National Computer Facility (NCF) and by NBIC from end of 2004.


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  Contact
For information, comments and/or suggestions on the CluSTr database, please email us at clustr@ebi.ac.uk

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Integr8
 

 
Integr8 is a browser for information relating to completed genomes and proteomes, based on data contained in Genome Reviews and the UniProt proteome sets..
 

 
InterPro
 

 
The InterPro database is an integrated documentation resource for protein families, domains and functional sites.
 

 
UniProt
 

 
UniProt is a central database of protein sequence and function created by joining the information contained in Swiss-Prot, TrEMBL, and PIR.
 
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