Chlorhexidine gluconate solution is prescribed by dentists for the treatment of gingivitis and mouth infections and for the reduction of dental plaque. Gingivitis is a medical term for inflammation of the gums characterized by redness, swelling, and bleeding upon probing. Although it is unknown exactly how the product works, it is believed to eliminate bacteria, which can cause dental plaque. Dental plaque is one of several causes of gingivitis.

Chlorhexidine Gluconate Facts
Brand name (manufacturer): Peridex (Procter & Gamble)

Type of drug: Oral rinse

Ingredient: Chlorhexidine as the gluconate salt

Dosage form: Mouthwash (11.6% alcohol)

Storage: Store at room temperature in a tightly closed, light-resistant container. Do not freeze.

Treatment

Treatment with chlorhexidine gluconate solution should begin following a thorough cleaning of your teeth by your dental practitioner.

Measure one-half fluid ounce (as marked in the cap of the product container) of chlorhexidine gluconate solution, and swish in the mouth for at least 30 seconds twice daily. Do not dilute it in water or other liquids. It should be used full strength. Chlorhexidine gluconate solution should be used after brushing and flossing.

Do not swallow chlorhexidine gluconate solution following use. It should be expectorated (spit out) after you rinse your mouth with it.

Do not rinse your mouth with water after using this medication; doing so may increase the bad taste of this medicine. And do not eat or drink for several hours after using the medication.

Side Effects

Minor: Irritation of the inside of the mouth can occur following use of this product. In addition, some patients may experience temporary taste disturbances. However, there have been no permanent taste disturbances reported with continued use of chlorhexidine gluconate. Other adverse effects from this chlorhexidine gluconate include tongue irritation and stomach upset.

Major: Be sure to tell your dentist about any side effects that are persistent or particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DENTIST about any inflammation and swelling of the parotid salivary gland.

Chlorhexidine may cause staining of the teeth and tongue. This staining will be more noticeable in patients who have a heavy accumulation of tartar. Usually, this staining is temporary and can be easily removed from most tooth surfaces with dental cleaning. Rarely, some persons, especially those with tartar, will have permanent stains. Use a tartar-control toothpaste and floss regularly to help reduce tartar buildup unless directed otherwise by your dentist.

Interactions

There do not appear to be any significant drug interactions with chlorhexidine gluconate. However, you should make sure that your dentist knows about all the medications you are currently taking.

Warnings
  • Tell your doctor and dentist about any reactions you have had to any medications, especially to chlorhexidine gluconate solution.

  • Chlorhexidine gluconate solution has not been fully evaluated for safety in children under the age of 18. Therefore, the medication should not be used by children who are in this age group.

  • To determine the effectiveness of treatment with chlorhexidine gluconate, it is advisable to have dental checkups at least every six months.

  • Be sure to tell your dentist if you are pregnant or are breast-feeding an infant. Scientific studies have not yet determined the effects of the administration of chlorhexidine gluconate to pregnant or nursing women or their babies. Therefore, use of this product during pregnancy or while breast-feeding should be carefully considered.