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Vector (biology) -- Traditionally in medicine, a vector is an organism that does not cause disease itself but which spreads infection by conveying pathogens from one host to another. Species of mosquito, for example, ... > full article

Gene therapy -- Gene therapy is the insertion of genes into an individual's cells and tissues to treat a disease, and hereditary diseases in particular. Gene therapy typically aims to supplement a defective mutant ... > full article

Tumor suppressor gene -- A tumor suppressor gene is a gene that reduces the probability that a cell in a multicellular organism will turn into a tumor cell. A mutation or deletion of such a gene will increase the probability ... > full article

Allele -- In genetics, an allele is any one of a number of viable DNA codings occupying a given locus (position) on a chromosome. Usually alleles are DNA sequences that code for a gene, but sometimes the term ... > full article

Huntington's disease -- The causative gene for Huntington's disease, HD, one of the first genes identified to cause an inherited disease, is located on chromosome 4. Huntington's disease is inherited in an autosomal ... > full article

BRCA1 -- BRCA1 (breast cancer 1, early onset) is a human gene that belongs to a class of genes known as tumor suppressor genes. Like many other tumor suppressor genes, BRCA1 regulates the cycle of cell ... > full article

Therapy dog -- Therapy Dog refers to a dog trained to provide affection and comfort to people in hospitals, retirement homes, nursing homes, mental institutions, schools, and stressful situations such as disaster ... > full article

BRCA2 -- BRCA2 is a human gene that is involved in the repair of chromosomal damage and belongs to a class of genes known as tumor suppressor genes. Tumor suppressor genes regulate the cycle of cell division ... > full article

Mutation -- In biology, mutations are changes to the genetic material (usually DNA or RNA). Mutations can be caused by copying errors in the genetic material during cell division and by exposure to radiation, ... > full article

Gene -- Genes are the units of heredity in living organisms. They are encoded in the organism's genetic material (usually DNA or RNA), and control the physical development and behavior of the organism. ... > full article

Trait (biology) -- In biology, a trait or character is a feature of an organism. The term phenotype is sometimes used as a synonym for trait in common use, but strictly speaking, does not indicate the trait, but the ... > full article

Spinal muscular atrophy -- Spinal Muscular Atrophy (SMA) is a term applied to a number of different disorders, all having in common a genetic cause and the manifestation of weakness due to loss of the motor neurons of the ... > full article

Myosin -- Myosins are a large family of motor proteins found in eukaryotic tissues. They are responsible for actin-based motility. Most myosin molecules are composed of both a head and a tail domain. The head ... > full article

Genetically modified organism -- A genetically modified organism (GMO) is an organism whose genetic material has been altered using techniques in genetics generally known as recombinant DNA technology. Recombinant DNA technology is ... > full article

Glioma -- A glioma is a type of primary central nervous system (CNS) tumor that arises from glial cells. The most common site of involvement of a glioma is the brain, but they can also affect the spinal cord, ... > full article

Encephalopathy -- Encephalopathy is a nonspecific term describing a syndrome affecting the brain. Generally, it refers to involvement of large parts of the brain (or the whole organ), instead of identifiable changes ... > full article

List of medical topics -- This is a list of medical ... > full article

DNA microarray -- A DNA microarray (also commonly known as gene chip, DNA chip, or biochip) is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA microarrays to measure the ... > full article

Rett syndrome -- Rett syndrome (or Rett's disorder) is a progressive neurological disorder that is classified as a pervasive developmental disorder by the DSM-IV. The symptoms of this disorder are easily confused ... > full article

Diabetes mellitus type 2 -- Diabetes mellitus type 2 (formerly called diabetes mellitus type II, non-insulin-dependent diabetes, NIDDM or adult-onset diabetes) is a long-term metabolic disorder that is primarily characterized ... > full article

 

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Summaries | Headlines

Researchers Developing Molecular Delivery Vehicles For Genetic Therapies (December 10, 2006) -- Researchers at New York University are working to develop molecular delivery vehicles that can be used to transport nucleic acids into diverse cell types, which may lead to eventual applications in ... > full story

Gene Therapy For Erectile Dysfunction Shows Promise In Clinical Trial (December 4, 2006) -- The first human trial of gene transfer therapy for erectile dysfunction (ED) indicates that gene therapy that lasts for months and eliminates the patient's need for on-demand drugs (such as Viagra ... > full story

Silencing The Cause Of Mad Cow Disease (December 4, 2006) -- BSE (more commonly known as mad cow disease) and CJD, a related disease in humans, are fatal neurodegenerative diseases caused by accumulation in the brain of an abnormally folded version (PrPsc) of ... > full story

Gene Therapy For Hereditary Lung Disease Advances (November 22, 2006) -- A clinical trial to evaluate the safety of using a so-called gene vector to deliver a corrective gene to 12 patients with a common hereditary disorder that causes lung and liver disease is completed ... > full story

Fusion Prostate Cancer: An Early Molecular Event Associated With Invasion (November 13, 2006) -- The presence of a gene fusion in prostate tumors is significantly associated with aggressive cancer, metastatic spread, and an increased probability of death, a team of researchers is ... > full story

Intravenous Gene Therapy Protects Normal Tissue Of Mice During Whole-body Radiation (November 9, 2006) -- Gene therapy administered intravenously could be used as an agent to protect vital organs and tissues from the effects of ionizing radiation in the event of large-scale exposure from a radiological ... > full story

Development Of New Polymer Delivery Vehicles For Gene Therapy (October 17, 2006) -- MIT scientists are reporting synthesis and laboratory tests of a promising new group of degradable polymer delivery vehicles for gene therapy. The polymers are improved versions of materials first ... > full story

Researchers Identify Gene Most Often Responsible For Commonest Form Of Congenital Blindness (October 4, 2006) -- A new study has identified the gene most often responsible for leber congenital amaurosis, the commonest form of congenital blindness. "This discovery represents a significant advance in the fight ... > full story

Jumping Gene Could Provide Non-viral Alternative For Gene Therapy (September 26, 2006) -- A jumping gene first identified in a cabbage-eating moth may one day provide a safer, target-specific alternative to viruses for gene therapy, researchers say. They compared the ability of the four ... > full story

Gene Therapy Study Takes Aim At Prostate Cancer (September 26, 2006) -- Researchers at Baylor College of Medicine (BCM) are hoping a new gene therapy that takes a gene called RTVP-1 directly into the prostate tumor will prove effective in preventing recurrence of the ... > full story

Gene Therapy Technique Reverses Type 2 Diabetes In Mice; Study Shows Promise Of Leptin (September 21, 2006) -- University of Florida researchers have discovered the appetite-controlling hormone leptin could also combat type 2 diabetes, a disease that has become a growing problem in the United States as more ... > full story

Mouse Strain With Gene Stutter Will Help Leukemia Research (September 20, 2006) -- Cancer researchers have developed a new strain of mice that should help reveal how an unusual change in a certain gene contributes to a particularly deadly form of acute myeloid leukemia. A study of ... > full story

< more recent summaries | earlier summaries >

Molecular Biology of the Gene, Fifth Edition
The long-awaited new edition of James D. Watson's classic text, Molecular Biology of the Gene, has been thoroughly revised and is published to coincide with the 50th anniversary of Watson and Crick's ... > read more

Human Molecular Genetics, Third Edition
Univ. of Newcastle, UK. Textbook focuses on the new knowledge in human molecular genetics since the Human Genome Project. Includes new chapters on cells and development and on functional genomics, ... > read more

Evolution in Four Dimensions : Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life (Life and Mind: Philosophical Issues in Biology and Psychology)
Ideas about heredity and evolution are undergoing a revolutionary change. New findings in molecular biology challenge the gene-centered version of Darwinian theory according to which adaptation ... > read more

Manipulating the Mouse Embryo: A Laboratory Manual
Mount Sinai Hospital, Toronto, Canada. Updated laboratory manual is a resource for technical and theoretical guidance. Contains a compilation of updated protocols and extensive background ... > read more

The Cure for All Cancers: Including over 100 Case Histories of Persons Cured
Cancer can now be cured, not just treated We are not accustomed to thinking about a cure for cancer. We think of remission as the only possibility. But this book is not about remission. It is about ... > read more

Family Therapy : An Overview (with InfoTrac)
FAMILY THERAPY provides a balanced presentation of the major theoretical underpinnings and clinical practices in the field. By presenting an overview of traditional and evolving viewpoints, ... > read more

Craniosacral Therapy
Craniosacral Therapy is the most practical, comprehensive textbook in this rapidly growing field of therapy involving the cranial bones, meningeal membranes, cerebrospinal fluids, and whole-body ... > read more

Biological Science (2nd Edition)
Infused with the spirit of inquiry, Freeman's Biological Science helps teach readers the fundamentals while introducing them to the excitement that drives the science. By presenting unifying concepts ... > read more

Inferring Phylogenies
Phylogenies (evolutionary trees) are basic to thinking about and analyzing differences between species. Statistical, computational, and algorithmic work on them has been ongoing for four decades, ... > read more

The Trigger Point Therapy Workbook: Your Self-Treatment Guide for Pain Relief, Second Edition
The first edition of this workbook is regarded as a classic in its field, and was the first book to introduce trigger point therapy to the general public as a self-care tool for alleviating chronic ... > read more

 
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