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In biotechnology, corporate success is a function of approved drugs, pipeline activity and positive cash flow. By those standards, one of the most successful firms in the industry is a 27-year-old Thousand Oaks, California outfit that was among the first developers of blockbuster biopharmaceuticals.
Amgen (NASDAQ: AMGN) is a biotechnology firm engaged in the discovery and manufacture of human therapeutics. It markets products in the areas of supportive cancer care, nephrology, inflammation, and oncology. Principal offerings include anemia treatments Aranesp and Epogen, rheumatoid arthritis drug Enbrel, and white blood cell stimulator Neupogen. Amgen has marketing alliances with Hoffmann-La Roche and Kirin. Competitors include Baxter International (NYSE: BAX) and Novartis (NYSE: NVS).
The stock popped last month on word an FDA advisory panel had rejected a proposal to set a specific target for red blood-cell levels in kidney-failure patients being treated with Aranesp, Epogen and Procrit. The latter is manufactured by Amgen, but sold by Johnson & Johnson (NYSE: JNJ). The panel's decision, if accepted by the FDA, could boost sales of the medications. Since the initial gain, the AMGN share price has been defining a bullish "flag" consolidation pattern. Prices frequently exit flags moving in the same direction they were traveling when they entered them. In this case, that would be to the upside.
Brokers recommend the stock with six "strong buys," six "buys," 18 "holds" and one "sell." The AMGN P/E ratio (16.19), PEG ratio (1.50), Price to Book ratio (3.73), Price to Cash Flow ratio (12.07), Price to Free Cash Flow ratio (16.98), Operating Margin (32.57%), Net Profit Margin (27.35%), Return on Assets (12.65%), Return on Investment (15.02%), Return on Equity (24.41%) and Net Income per Employee ($203.25k) compare favorably with industry, sector and S&P 500 averages. Institutions hold about 76% of the outstanding shares. The stock is one of those used to calculate the S&P 100, S&P 500 and Nasdaq 100 Indexes. Over the past 52 weeks, it has traded between $48.30 and $77. A stop-loss of $48.65 looks good here. Note that the firm is expected to release third quarter results on October 25, after the close.
"An annual infusion of Novartis AG's Reclast after a mild hip fracture helps prevent another broken bone and prolongs life in elderly patients, researchers said. The findings released today by the New England Journal of Medicine should bolster use of the drug. It generated almost $1.3 billion in 2006 under the name Zometa for treating cancer that has spread to the bone. U.S. regulators approved Reclast last month for postmenopausal women with osteoporosis."
Although the study was funded by NVS, there were few disputes about the results. There was also a limited controversy with some doctors declining to participate, saying they didn't feel right giving certain at risk patients in their 70s a placebo instead of one of the many exisiting alternatives
For some companies, focusing on a single specialization is the best way to build a reputation, leverage resources and maximize effectiveness. There is a Mont-Saint-Hilaire, Quebec outfit that has followed that path to leadership in the field of gastroenterology-related pharmaceuticals.
Axcan Pharma (NASDAQ: AXCA) is engaged in the development and sale of pharmaceutical products for the treatment of gastrointestinal diseases and disorders. Products include medicines for exocrine pancreatic insufficiency diseases; cholestatic liver diseases; inflammatory bowel diseases; gastric duodenal ulcers; and irritable bowel syndrome. The firm also owns the global rights to Photofrin, a drug with applications to esophageal, gastric and lung cancers. Other products include caloric supplements for cystic fibrosis patients and over-the-counter antacids. The company sells its products primarily to wholesale drug companies and distributors. Novartis (NYSE: NVS) is a major competitor.
The firm pleased investors last week, when it reported fiscal Q3 EPS of 36 cents and revenues of $92.3 million. Analysts had been expecting 26 cents and $81.6 million. Management also guided FY07 revenues to $335-$343 million, versus Street consensus of $324.74 million.
Countrywide Financial (NYSE: CFC) volatility aggressive; draws on $11.5 billion credit facility. CFC, the largest U.S. home mortgage lender, is down to $18.99 in pre-open trading, below its close of $21.29. CFC announced "it has supplemented its funding liquidity position by drawing on an $11.5 billion credit facility." CFC September option implied volatility of 164 is above its 26-week average of 56 according to Track Data, indicating larger price fluctuations.
BHP Billiton (NYSE: BHP) implied volatility elevated at 41. BHP, the world's biggest mining company, said there was no impact at its Atamina copper mine from Peru's largest earthquake in more than 30 years. BHP overall option implied volatility of 41 is above its 26-week average of 34 according to Track Data, suggesting larger price fluctuations.
Novartis (NYSE: NVS) implied volatility elevated at 28. NVS, engaged in research, development, manufacture and marketing of medicines, closed at $52.17. Dow Jones reported "a tie up of NVS and Bayer (NYSE: BAY) seems unlikely, says WestLB." NVS overall option implied volatility of 28 is above its 26-week average of 23 according to Track Data, suggesting larger price risk.
MOST NOTEWORTHY: Novartis AG (NVS), Intel (INTC), Total S.A. (TOT), Syniverse Holdings, Inc (SVR) and Kindred Healthcare (KND) were today's noteworthy downgrades:
Merrill cut Novartis (NYSE: NVS) to Neutral from Buy based on a lack of near-term catalysts. Credit Suisse downgraded shares of the company to Underperform from Neutral on expectations of slowing sales growth in 2H07.
JMP Securities downgraded Intel (NASDAQ: INTC) to Market Perform from Outperform based on valuation and lower estimates.
JP Morgan cut Total S.A. (NYSE: TOT) to Neutral from Overweight on valuation.
Syniverse (NYSE: SVR) was cut to Strong Sell from Sell at Matrix USA as competition in North America is creating a cut in Network Services and Number Portability Services revenue.
Kindred Healthcare (NYSE: KND) was cut to Underperform from Market Perform at Wachovia based on valuation...
OTHER DOWNGRADES:
DaVita (NYSE: DVA) was downgraded to Hold from Buy at Deutsche Bank.
A 50% cut in health insurance premiums would only reduce the number of uninsured Americans by 3%, estimates a Rand study out Monday, which suggests that incentives and government tax cuts won't lead to universal coverage. Instead, a federal requirement that all people have insurance may be the only way to achieve such a goal, says study author Susan Marquis, an economist at Rand, a think tank.
Go Organic, For Less Produced without pesticides and other chemicals, organic produce, meat and dairy products can cost 50% to 100% more than their conventional counterparts. Despite those mark-ups, studies touting the health and environmental benefits of organic foods have made them more popular than ever before. More than 70% of consumers have at least one organic product on their shopping list. Here are five tips for going organic for less. Buy Organic Without Breaking the Bank
Google Map Mashups a Help for Homebuyers
Since Google made its maps available for customization last year, savvy programmers have created thriving businesses by adding layers of information. Two examples: real estate site Zillow and Hotel World Map. But making these so-called map mashups has been beyond the reach of the average user. So in May, GeoCommons was launched, a cartographic portal where users can easily create their own mashups. The site has 2 billion pieces of localized data -- from census figures and school district budgets to water-contamination and traffic-congestion hot spots -- and it is rapidly adding more.
Banks are having trouble finding qualified tellers as they expand their branch networks. The entry-level position now demands greater marketing abilities, sparking a labor crunch that has forced employers to boost wages and training.
Baby food maker Gerber has announced the recall of half a million packages of organic rice and oatmeal cereal. According to the company, the cereal poses a choking hazard. Lumps in the cereal may not dissolve properly, and babies may choke on the solid particles that remain even after milk or water has been added.
The recall was announced late on Friday but is getting more attention today. Gerber is owned by Novartis AG (NYSE: NVS), the Swiss pharmaceutical and consumer health giant. So far, the recall does not appear to have hurt the company's stock.
For parents, of course, it's another matter. The thought of children being harmed by something as basic and essential as food is deeply disturbing. To make matters worse, the recall involves organic baby food, which to parents (or at least this one) promises greater safety and health in exchange for a higher price.
In its press release, Gerber says that it "has received choking complaints, but no reports of injury." The cereal in question was distributed in the United States, Puerto Rico and the Caribbean. For more information, see the press release posted on Gerber's website.
This story was inspired by "Hal C" who thought out loud yesterday in a comment following It's an 'I told you so' day for the stock market bears. He wrote, "The continued upward momentum of this Market is astounding to me. The kind of problems we have today would have ko'd many previous upward trends." This raised some great questions indeed, and he is not alone in his sentiments.
Here are a few things to think about that are affecting the stock market and the economy in general.
1) The economy has globalized and there are many more foreign companies you can invest in through American Depository Receipts (ADR) or the like. Three of my last five stock buys were Novartis AG ADS (NYSE: NVS - Swiss) Tata Motors LTD (NYSE: TTM - Indian) and Cemex SAB DE CV (NYSE: CX- Mexican) All three were subjects of my Chasing Value section. All three are doing well and do not depend on the American consumer. The percentage of the United States stock market that is foreign is ever growing and so our exchanges are now marching to the beat of a different drummer. It can move upward when we are hurting.
The development of new information technologies leads to fresh opportunities for businesses to expand and serve their customer bases. There is a Cambridge, Massachusetts firm that rides the crest of the IT wave, helping companies take full advantage of those opportunities.
Sapient Corporation (NASDAQ: SAPE) provides business, marketing and technology consulting services. The firm's design and implementation expertise are used by information-based businesses and government agencies with needs in e-commerce, customer relationship management, high volume transaction processing, online supply chain development and knowledge management. Clients include BP (NYSE: BP), Harrah's Entertainment (NYSE: HET), Novartis (NYSE: NVS), Sony (NYSE: SNE), Staples (NASDAQ: SPLS), United Parcel Service (NYSE: UPS) and Verizon Communications (NYSE: VZ).
The firm pleased investors last week, when it reported Q1 EPS of one cent and revenues of $121.3 million. Analysts had been looking for a penny and $117.4 million. Management also guided Q2 revenues to $126 million ($122.61M consensus). RBC Capital Markets and UBS subsequently declared the issue a "buy" and issued price targets in the $9.25-$10.00 range. The stock popped into a bullish "flag" formation on the news. Prices frequently exit flags moving in the same direction they were traveling when they entered them. In this case, that would be to the upside.
Brokers recommend the issue with two "strong buys," four "buys," four "holds" and two "sells." Analysts see a 72% growth rate, through the next year. The stock's Price to Sales ratio (2.37), Price to Book ratio (4.58) and Sales Growth rate (39.0%) compare favorably with industry, sector and S&P 500 averages. Institutional investors hold about 61% of the outstanding shares. Over the past 52 weeks, SAPE has traded between $4.35 and $8.26. A stop-loss of $6.60 looks good here.
The morning started with positive economic data as Consumer Spending and Personal Incomes were up 0.6% for February, beating expectations of 0.3% increases. Ultimately markets ended drifting sideways to close in mixed slightly positive territory. This was the last trading day of the first quarter; and although there was a big drop with the China jitters, the Dow Jones Industrial Average only lost 0.9% and the S&P 500 actually made a tiny 0.1% gain.
The NYSE had volume of 2.8 billion shares with 1,802 shares advancing while 1,456 declined for a loss of 17.26 points to close at 9,261.82. On the NASDAQ, 2.1 billion shares traded, 1,723 advanced and 1,315 declined for a gain of 3.76 to 2421.64.
Stocks moving today included: Dendreon Corp (NASDAQ: DNDN) shot up $7.71 (148%) to $12.93 after the FDA approved its prostate drug. Hansen Natural (NASDAQ: HANS) rose $1.9 (5%) to $37.88 on an upgrade by JP Morgan. Novartis (NYSE: NVS) fell $2.26 (-4%) to $54.63 on news it was stopping a constipation drug Zelnorm. Smithfield Foods (NYSE: SFD) gained $0.82 (3%) to $29.95.
Texas Instruments Incorporated (NYSE:TXN) mid-quarter update conference call at 5pm. Note that Stifel just upgraded Texas Instruments to Buy from Hold as they believe the mid-quarter update will show improving trends.
Tuesday March 13
Goldman Sachs Group Inc. (NYSE:GS) to report Q4 earnings; conference call at 4:30pm.
Qualcomm Incorporated (NASDAQ:QCOM) to hold annual shareholder meeting at 11:30am.
PDUFA Date for GlaxoSmithKline plc ADR's (NYSE:GSK) Tykerb, a breast cancer drug.
Wednesday March 14
Retailers Hot Topic Inc. (NASDAQ:HOTT) and Zumiez Inc (NASDAQ:ZUMZ) to report earnings. Hot Topic's Q4 conference call is at 4:30pm, Zumiez's Q4 conference call is at 5pm.
PDUFA Date for Novartis AG ADS's (NYSE:NVS) Tekturna, a treatment for high blood pressure.
Thursday March 15
Bayer AG ADS (NYSE:BAY) to report Q4 earnings; conference call at 6am.
Six Flags Inc (NYSE:SIX) to report Q4 earnings; conference call at 4pm. Note that earlier this week, Cramer specified Six Flags as a stock he was bullish on during the "Lightning Round" of his Mad Money television show.
Friday March 16
IMAX Corp (NASDAQ:IMAX) to report Q4 earnings; conference call at 8:30am.
AnnTaylor Stores Corporation (NYSE:ANN) to report Q4 earnings; conference call at 8:30am.
MOST NOTEWORTHY: Novartis AG (NVS), Barnes & Noble, Inc (BKS), Altria Group (MO) and Advanced Micro Devices (AMD) were some of today's more notable upgrades:
Credit Suisse upgraded Novartis AG (NYSE: NVS) to Neutral from Underperform on valuation and the approval of its drug Tekturna.
Merrill Lynch upgraded shares of Barnes & Noble, Inc (NYSE: BKS) to Neutral from Sell on valuation.
Deutsche Bank believes the recent weakness in Altria Group (NYSE: MO) presents a buying opportunity given the potential to unlock value, upgrading shares to Buy from Hold.
JMP Securities upgraded shares of Advanced Micro Devices Inc (NYSE: AMD) to Market Outperform from Market Perform following checks that indicate the company's next-generation "Barcelona" quad-core server chip and next-generation low-power mobile PC processor chip is exhibiting excellent power, performance, scalability, and price/performance characteristics at key OEM customers.
OTHER UPGRADES:
ThinkEquity upgraded Microchip Technology Inc (NASDAQ: MCHP) to Accumulate from Source of Funds following the company's improved guidance.
Morgan Stanley upgraded Eni SpA (NYSE: E) to Equal-Weight from Underweight as they believe management made it clear that the dividend is sustainable and a large-scale acquisition is not forthcoming.
JP Morgan upgraded Deutsche Telekom AG (NYSE: DT) to Neutral from Underweight citing management's new focus on customer service and expectation's for modest growth for the upgrade.
AG Edwards upgraded Anheuser-Busch Companies Inc (NYSE: BUD) to Buy from Hold.
Morgan Joseph upgraded Boyd Gaming Corp (NYSE: BYD) to Buy from Hold based on key markets the company operating in and its diversification.
Bernstein upgraded Cablevision Systems Corp (NYSE: CVC) upgraded to Outperform from Market Perform.
Major European stock markets are up today between .5% to 1%, following the lead Asia set this early morning. Trading was reported to be brisk on all major markets. Good news came from Swiss drugmaker Novartis (NYSE:NVS) as it received an approval for a blood pressure medication----which will be in demand if these market fluctuations continue.
International Power (NYSE:IPR) of the United Kingdom led the way on the FTSE index as it reported an excellent profits report and lifted its current dividend by 75%. This stock trades on the NYSE as an ADR as well as in the United Kingdom. Rising power prices were attributed to the profit surge.
On the slightly negative side, France Telecom ( FTE) was off less than 1% as they reported a slump in profits and indicated that 2007 would not bring any dividend increase. The CAC 40 however, was still positive on the day as investors were not surprised by the France Telecom report.
Traders in London are anxiously awaiting the open of the US markets today as many feel the stability of US Treasuries today, globally, will stabilize if not begin to lift the bell-weather US stock markets.
XM Satellite Radio Holdings Inc (NASDAQ: XMSR) to report Q4 earnings; conference call at 10am. Analysts will review XM's overall subscribers, new subscribers, retention rates, average monthly fees, pricing plans, new broadcast content agreements, marketing strategy, operating costs, sector position, and margins. Equally significant, Wall Street will also pay very close attention to management's operational posture moving forward, in light of its proposed merger agreement with Sirius Satellite Radio Inc (NASDAQ: SIRI).
Tuesday February 27
Sirius Satellite Radio to report Q4 earnings; conference call at 8am. The concerns for Sirius mirror the previously mentioned concerns for XM.
Wednesday February 28
PDUFA Date for Novartis AG ADS's (NYSE: NVS) Galvus, an innovative oral therapy for people with type 2 diabetes.
Thursday March 1
Echostar Communications Corporation (NASDAQ: DISH) to report Q4 earnings; conference call at 12pm. Analysts will focus on Echostar's success at adding value to its offerings, amid intensifying competition from digital cable and communications companies offering TV services.
PDUFA date for New River Pharmaceuticals Inc (NASDAQ: NRPH) and Shire plc ADS's (NASDAQ: SHPGY) Vyvanse, for the treatment of Attention Deficit Hyperactivity Disorder [ADHD].
PDUFA date for Merck Serono SA ADS's (NYSE: SRA) Serostim, a treatment for AIDs wasting.
Friday March 2
THQ Inc (NASDAQ: THQI) to hold analyst meeting in San Fransisco, CA.
Merck & Co. (NYSE:MRK) must now attract glass-is-half-full types as stockholders.
Who else but supreme optimists would buy stock in a drug maker facing more than 27,000 lawsuits regarding Vioxx, not including the Pennsylvania woman who recently dropped hers? Their faith that Merck will beat these cases is evident in the stock price.
Shares of Merck have jumped more than 39% over the past year, outperforming Pfizer Inc. (NYSE:PFE) Novartis AG (NYSE:NVS) and Schering-Plough Corp. (NYSE:SGP). Granted, beating Pfizer isn't that much of a victory, but still, that's a decent move.
Wall Street, which is awaiting Merck's fourth quarter results Jan. 30, expects the stock to climb further. The median target for Wall Street analysts is $48.50, according to Thomson Financial. Opinion, though, remains divided. Eleven analysts consider the shares either a strong buy or buy, 10 rate it a hold, and 3 a sell.
Merck has already said earnings this year are going to be lackluster and Wall Street is taking the company at its word. Analysts are forecasting earnings of 50 cents on sales of $5.38 billion, according to Thomson Financial. A year earlier, the company had a profit of 64 cents and revenue of $5.77 billion.
As Douglas McIntyre pointed out, Merck needs to convince investors that it's not Pfizer in the wake of that company's failed anti-cholesterol drugs. The Whitehouse, New Jersey-based company said last month that it will seek approvals for three important drugs this year and would have four more drugs in late-stage trials by mid-2007.
Also check out some other earnings reports that we're following, and let us know your thoughts on earnings expectations.