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Researchers from Yale have discovered how bacteria combat the effects of fluoride in toothpaste. Bacteria contain molecules called riboswitches which detect the presence of fluoride and alert bacteria to mount defenses against the substance. Riboswitches are RNA messages that activate certain genes. These molecular switches activate bacterial genes that code for processes that promote tooth decay.
According to researcher Ronald Breaker, "These riboswitches are detectors made specifically to see fluoride. If fluoride builds up to toxic levels in the cell, a fluoride riboswitch grabs the fluoride and then turns on genes that can overcome its effects." The researchers believe that it may be possible to target the bacteria's defense mechanisms to make fluoride more toxic to them.
Learn more about this study:
- How Bacteria Fight Fluoride in Toothpaste Science Daily
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