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National Center for Biotechnology Information
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NCBI Announcements

  • Updates to assembly alignments for NCBI Remap service

    Oct 10, 2014

    NCBI has updated its assembly alignment software (now version 1.7), which generates the alignments used for Remap, NCBI's coordinate remapping service. The improvements include: better handling of alternate loci and fix patches, improved alignments in regions of copy number variation, better recognition of sequence regions that are unaltered between two versions of a WGS assembly, incorporation of fixes to BLAST including bugs affecting alignments around regions with multiple mismatches and indels, and assorted other quality improvements.

  • New NCBI Insights blog: Sequence updates in human assembly GRCh38: improving gene annotation

    Oct 9, 2014

    The latest blog post on the NCBI Insights blog continues the discussion of GRCh38. This time, the blog post focuses on how GRCh38 improved gene annotation.

  • Zebrafish (Danio rerio) GRCz10 now annotated

    Oct 8, 2014

    Zebrafish (Danio rerio) GRCz10 is annotated! GRCz10 is an update to the Zv9 assembly, released by the Genome Reference Consortium (GRC), which now manages this reference genome assembly in addition to those for human and mouse. GRCz10 includes more than 1,000 new clone sequences and improvements to the order and orientation of assembly sequences.

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