What are the functions of microtubules[Edit]
There are 4 main functions of microtubules:
1.To form an architectural framework that establishes the overall polarity of the cell by influencing the organization of the nucleus, organelles and other cytoskeleton components.
2. To form the spindle apparatus and ensure the proper segregation of duplicated chromosomes into daughter cells during cell division (i.e. cytokinesis). The spindle apparatus also regulates the assembly and location of the actin-rich contractile ring that pinches and separates the two daughter cells.
3.To form an internal transport network for the trafficking of vesicles containing essential materials to the rest of the cell. This trafficking is mediated by microtubule associated proteins (MAPs) with motor protein activity such as Kinesin and Dynein.
4. To form a rigid internal core that is used by microtubule-associated motor proteins to generate force and movement in motile structures such as cilia and flagella. A core of microtubules in the neural growth cone and axon also imparts stability and drives neural navigation and guidance.
2. To form the spindle apparatus and ensure the proper segregation of duplicated chromosomes into daughter cells during cell division (i.e. cytokinesis). The spindle apparatus also regulates the assembly and location of the actin-rich contractile ring that pinches and separates the two daughter cells.
3.To form an internal transport network for the trafficking of vesicles containing essential materials to the rest of the cell. This trafficking is mediated by microtubule associated proteins (MAPs) with motor protein activity such as Kinesin and Dynein.
4. To form a rigid internal core that is used by microtubule-associated motor proteins to generate force and movement in motile structures such as cilia and flagella. A core of microtubules in the neural growth cone and axon also imparts stability and drives neural navigation and guidance.