Published: April 2015
Editors: Raymond L. Benza, MD; Paul A. Corris, MB, FRCP; Myung H. Park, MD; Patricia Uber, PharmD; James K. Kirklin, MD
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Contributors (PDF)
Table of Contents
SECTION I: PULMONARY ARTERIAL HYPERTENSION
Introduction - PAH: A Global Disease
Chapter 1: Classification and Epidemiology
Chapter 2: Genetics and Pathophysiology - Updates with Focus on Translational Approaches
Chapter 3: PAH Associated with Underlying Systemic Conditions
A. PAH and Connective Tissue Disease
B. PAH and Infectious Diseases
C. PAH and Congenital Heart Disease
D. PAH in Portopulmonary Hypertension
Chapter 4: Diagnosis of Pulmonary Arterial Hypertension
SECTION II: THE RIGHT VENTRICLE
Introduction - Nomenclature of Right Heart Failure
Chapter 5: Embryology, Anatomy and Function of Right Ventricle
Chapter 6: Mechanisms of Right Ventricular Failure
Chapter 7: Management of Right Heart Failure
Chapter 8: Determination of Right Ventricular Function in PAH
SECTION III: MEDICAL THERAPIES FOR PAH
Introduction - The Journey of Medicines for PAH
Chapter 9: Therapies for PAH in the Developed and Developing World
Chapter 10: Combination Approach to Treatment for PAH
Chapter 11: Perspectives on Current Utilization of PAH Therapies and Future Treatments
Chapter 12: Assessing Prognosis and Response to Therapy
SECTION IV: PULMONARY HYPERTENSION ASSOCIATED WITH HEART AND LUNG DISEASE
Introduction - Effect of Pulmonary Hypertension in Systemic Disorders
Chapter 13: Pulmonary Hypertension in Left Heart Disease - Systolic, Diastolic, Valvular
Chapter 14: Pulmonary Hypertension in Parenchymal Lung Disease and Sleep Disorder
Chapter 15: Chronic Thromboembolic Pulmonary Hypertension
SECTION V: PERIOPERATIVE MANAGEMENT OF PATIENTS WITH PULMONARY HYPERTENSION
Introduction - Impact of Pulmonary Hypertension in Perioperative Settings
Chapter 16: Risk Assessment
Chapter 17: Anesthesia for Patients with Severe Pulmonary Hypertension and Right Heart Failure: Effects of Anesthetic and Resuscitation Drugs
SECTION VI: SURGICAL AND PERCUTANEOUS MODALITIES FOR PULMONARY HYPERTENSION AND RIGHT HEART FAILURE
Introduction - Unique Challenges in Mechanical Support for PH and Right Heart Failure
Chapter 18: Mechanical Ventilation in the Perioperative Period: Effects on the Right Ventricle
Chapter 19: Interventional Approaches for PAH
Chapter 20: Pulmonary Thromboendarterectomy
Chapter 21: Mechanical Circulatory Support for Right Heart Failure
Chapter 22: Lung Transplantation in Pulmonary Hypertension