- X-men legends 2 (GCN)
- X-Men Legends II: Rise of Apocalypse (GCN)
- X-Men Origins: Wolverine (DS)
- X-Men: Destiny (Wii)
- X-Men: Next Dimension (GCN)
- X-Men: The Official Game (DS)
- X-Men: The Official Game (GCN)
- X-Morph: Defense (Switch eShop)
- X-Scape (DSiWare)
- X2: Wolverine's Revenge (GCN)
- Xavier (Wii U eShop)
- Xeno Crisis (Switch)
- Xenoblade Chronicles (Wii)
- Xenoblade Chronicles 2 (Switch)
- Xenoblade Chronicles 2: Torna - The Golden Country (Switch)
- Xenoblade Chronicles 3D (New 3DS)
- Xenoblade Chronicles X (Wii U)
- Xenoblade Chronicles: Definitive Edition (Switch)
- Xenon 2 Megablast (GB)
- Xenon Racer (Switch)
- Xenon Valkyrie+ (Switch eShop)
- Xenoraid (Switch eShop)
- XenoRaptor (Switch eShop)
- Xenosaga I & II (DS)
- Xeodrifter (3DS eShop)
- Xeodrifter (Switch eShop)
- Xeodrifter (Wii U eShop)
- Xevious (NES)
- XG Blast (DS)
- XGRA: Extreme-G Racing Association (GCN)
- Xiaolin Showdown (DS)
- XIII (GCN)
- Xmas Puzzle (WiiWare)
- Xtreme Club Racing (Switch eShop)
- Xtreme Sports (GBC)
- XType Plus (Wii U eShop)