Cancer News

April 24, 2020

Top Headlines

Sars-CoV-2 virus illustration (stock image). | Credit: (c) dottedyeti / stock.adobe.com

Researchers Identify Cells Likely Targeted by COVID-19 Virus

Apr. 22, 2020 Researchers have identified specific types of cells that appear to be the targets of the SARS-Cov-2 coronavirus that is causing the ... read more

HeLa cervical cancer cells (stock image). | Credit: (c) heitipaves / stock.adobe.com

Study Finds Evidence for Existence of Elusive 'Metabolon'

Apr. 16, 2020 Scientists have long hypothesized the existence of enzyme clusters, or 'metabolons,' in facilitating various processes within cells. Researchers have now directly observed ... read more

COVID-19 Drug Lead Treatments Identified

Apr. 9, 2020 An international team of researchers has tested more than 10,000 compounds to identify six drug candidates that may help treat COVID-19. The research tested the efficacy of approved drugs, drug ... read more

Chemists Working on Drugs to Treat COVID-19

Apr. 6, 2020 In the wake of the novel coronavirus pandemic, chemists have focused on searching for drugs to treat COVID-19. One group identified the antiviral drug remdesivir as a viable medicine to treat ... read more

Latest Headlines

updated 3:16pm EDT

Human Uterus Colonized by Clones With Cancer-Driving Mutations That Arise Early in Life

Apr. 22, 2020 Many cells in the inner lining of the uterus carry 'cancer-driving' mutations that frequently arise early in life, report scientists. The research ... read more

Game Theory Suggests More Efficient Cancer Therapy

Apr. 23, 2020 Mathematicians are using game theory to model how this competition could be leveraged, so cancer treatment -- which also takes a toll on the patient's body -- might be administered more sparingly, ... read more

How Cancer Cells Don Their Invisibility Cloaks

Apr. 21, 2020 Immunotherapy drugs that target a protein called programmed death ligand 1 (PD-L1) on the surface of cancer cells have quickly become a mainstay to treat many forms of cancer, often with dramatic ... read more

Scientists Explore Using 'Own' Immune Cells to Target Infectious Diseases Including COVID-19

Apr. 21, 2020 The engineering of specific virus-targeting receptors onto a patient's own immune cells is now being explored by scientists as a potential therapy ... read more

Researchers Repurpose Classic Chemotherapy Drug to Overcome Cancer Therapy Resistance

Apr. 20, 2020 Drug resistance is a major obstacle in cancer treatment -- leading to relapse for many patients. In a new study, researchers report on a promising ... read more

Finding Leukemia's Weakness Using Genome-Wide CRISPR Technology

Apr. 20, 2020 Researchers have used CRISPR technology to identify key regulators of aggressive chronic myeloid ... read more

Turning on the 'Off Switch' in Cancer Cells

Apr. 20, 2020 A team of scientists has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer. The discovery marks a critical ... read more

Stem Cells in Human Embryos Commit to Specialization Surprisingly Early

Apr. 17, 2020 The point when human embryonic stem cells irreversibly commit to becoming specialized has been identified by ... read more

Cancer Drug Resistance Study Raises Immune Red Flags

Apr. 17, 2020 Once a cancer patient's tumors develop resistance to chemotherapy, the prognosis can be poor. However, inhibiting a key gene involved in multidrug resistance, MDR1, has not improved outcomes. A new ... read more

Mysterious Tuft Cells Found to Play Role in Pancreatitis

Apr. 17, 2020 Scientists have uncovered the formation of tuft cells during pancreatitis and the surprising role of these cells in immunity, using mouse models of pancreatitis. The findings could lead to the ... read more

Earlier Headlines

Experts Issue Guide on Lung Cancer Screening, Management During COVID-19

Apr. 23, 2020 A new expert panel consensus statement provides guidance to clinicians managing lung cancer screening programs and patients with lung nodules during the COVID-19 ... read more

New Clues to Predict the Risks Astronauts Will Face from Space Radiation on Long Missions

Apr. 16, 2020 Researchers used a novel approach to test assumptions in a model used by NASA to predict health risks for ... read more

New 'Toolbox' for Urological Cancer Detection

Apr. 16, 2020 Researchers have developed a new method for biomarker discovery of urological cancers. The method enables timely diagnosis and treatment of cancer. Urological cancers include e.g. prostate, bladder ... read more

Aspirin Linked to Reduction in Risk of Several Cancers of the Digestive Tract

Apr. 15, 2020 The largest and most comprehensive analysis to date of the link between aspirin and cancers of the digestive tract has shown that it is associated not only with a significant reduction in the risk of ... read more

Bile Metabolite of Gut Microbes Boosts Immune Cells

Apr. 15, 2020 A new study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells--immune cells that suppress autoimmune reactions and ... read more

Experimental Drug Offers Hope for Preventing Cancer Relapse

Apr. 14, 2020 A drug that is well-tolerated in patients and prevents cancer coming back in mice has been ... read more

Mouse Study Shows How Advancing Glioma Cells Scramble Brain Function, Blood Flow

Apr. 14, 2020 The first sign of trouble for a patient with a growing brain tumor is often a seizure. Such seizures have long been considered a side effect of the tumor. But now a joint team of Columbia engineers ... read more

Switching on a Key Cancer Gene Could Provide First Curative Treatment for Heart Disease

Apr. 14, 2020 Researchers trying to turn off a gene that allows cancers to spread have made a surprising U-turn. By making the gene overactive and functional in the hearts of mice, they have triggered heart cell ... read more

Tumors Hijack the Cell Death Pathway to Live

Apr. 13, 2020 Cancer cells avoid an immune system attack after radiation by commandeering a cell signaling pathway that helps dying cells avoid triggering an immune response, a new study ... read more

Tailoring Treatment for Triple-Negative Breast Cancer

Apr. 13, 2020 Triple-negative breast cancer is a particularly aggressive form of the disease with no specific treatment. Researchers discovered that, in contrast to many other cancer types, activation of the ... read more

Researchers Describe Possible Mechanism for Link Between Obesity and Breast Cancer

Apr. 13, 2020 It is widely accepted that higher levels of body fat increase the risk of developing breast cancer, as well as other cancers. A new article proposes a unique theory that a protein secreted by fat ... read more

PARP Inhibitor Drugs Can Be 'Tuned' for Better Killing of Tumor Cells

Apr. 10, 2020 A prospective 'PARP inhibitor' drug that has struggled to show effectiveness in clinical trials against cancers can be structurally modified to greatly increase its power to kill tumor ... read more

Mathematical Model Predicts Patient Outcomes to Adaptive Therapy

Apr. 9, 2020 Researchers provide a closer look at a mathematical model and data showing that individual patient alterations in the prostate-specific antigen (PSA) biomarker early in cancer treatment can predict ... read more

Identical Mice, Different Gut Bacteria, Different Levels of Cancer

Apr. 9, 2020 Some types of gut bacteria are better than others at stimulating certain immune cells, specifically CD8+ T cells. And while these CD8+ T cells normally help protect the body against cancer, ... read more

Optical Imaging Technology May Help Surgeons Better Treat Cancer, Brain Diseases

Apr. 9, 2020 Researchers created technology that uses optical imaging to better help surgeons map out tumors in the body and help them understand how certain diseases affect activity in the ... read more

Critical Protein in Cancer Treatment-Related Heart Damage

Apr. 9, 2020 Researchers showed that a protein named FOXO1 plays a critical role in heart damage resulting from treatment with anthracycline chemotherapy drugs. Using a rodent model, they also demonstrated that ... read more

Missing BAP1 Gene Associated With Immunosuppressive Molecules in Uveal Melanoma

Apr. 9, 2020 A new study reveals that tumors lacking a protein called BAP1 have an ineffective immune reaction against cancer, thus rendering immunotherapies ineffectual, particularly in uveal melanomas (UM). The ... read more

Drug Shows Promise in Reversing Kidney Damage Caused by Lupus

Apr. 8, 2020 A drug used for cancer therapy has shown promise in reversing kidney damage caused by systemic lupus erythematosus (SLE, or lupus), according to a Yale-led study published April 8 in the journal ... read more

Cancer Mutation in Dual Role

Apr. 8, 2020 Analyses of cell signals provide insight into the origin of severe inflammatory symptoms that appear in various types of blood cancer and point to possible therapeutic approaches: In around ... read more

Observing the Internal 3D Structure of the Nipple to Understand and Fight Breast Cancer

Apr. 8, 2020 Researchers employed X-ray dark-field computed tomography to create three-dimensional renderings of the internal structure of the human nipple, thereby elucidating its varied arrangements. Their ... read more

Thursday, April 23, 2020