... heterozygote advantage in both sexes, (b) that there is heterozygote advantage in one sex and directional selection in the other, and (c) that there is sexually antagonistic selection, i.e. that the allele that feminises males decreases ...
... Heterozygote Advantage (Overdominance) All of the selection models that we have discussed so far lead to the even- tual fixation of one allele or the other and, as a result, reduce the genetic variation in the population. On the other ...
... heterozygote advantage: it is very difficult to prove heterozygote advantage when homozygotes are not lethal, but this is precisely the situation where heterozygote advantage is most conspicuous. In other words, heterozygote advantage ...
... heterozygote advantage as a possible explanation for the maintenance of the extensive allozyme variation he and Hubby documented in D. pseudoobscura . However , to maintain variation with heterozygote advantage at a large number of loci ...
... heterozygote advantage at individual gene loci is prevalent in natural populations . The enthusiasm toward the omnipresence of heterozygote advantage was spurred by Lerner's ( 1954 ) proposal of genetic homeostasis ' . According to him ...
... heterozygote advantage, possibly through a greater resistance of carriers to infectious disease. If continued over many generations, even a small degree of heterozygote advantage can be enough to change allele frequencies significantly ...
... heterozygote advantage underlies the observed levels of genetic variation. Interestingly, this model is unique among the classical, one-locus, two-allele models of constant viability selection in maintaining both alleles at a stable ...
... heterozygote advantage and frequency-dependent selection. Heterozygote Advantage If individuals who are heterozygous at a particular locus have greater fitness than do both kinds of homozygotes, they exhibit heterozygote advantage. In ...
... Heterozygote advantage is responsible for many cases of potentially harmful genes being maintained at a finite frequency in a population. The classic example of heterozygote advantage is sickle-cell gene, where homozygote individuals ...