Entry
Symbol
cobB-cbiA
Name
Pathway
Module
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
M00925 Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide
Reaction
R05815 cobyrinate:L-glutamine amido-ligase (ADP-forming)
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase
Enzymes [BR:ko01000 ]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.9 hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)
K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase
6.3.5.11 cobyrinate a,c-diamide synthase
K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase
BRITE hierarchy
Other DBs
Genes
» show all
Taxonomy UniProt
Reference
Authors
Roessner CA, Huang KX, Warren MJ, Raux E, Scott AI.
Title
Isolation and characterization of 14 additional genes specifying the anaerobic biosynthesis of cobalamin (vitamin B12) in Propionibacterium freudenreichii (P. shermanii).
Journal
Reference
Authors
Fresquet V, Williams L, Raushel FM
Title
Mechanism of cobyrinic acid a,c-diamide synthetase from Salmonella typhimurium LT2.
Journal
Sequence
LinkDB
All DBs