(Translated by https://www.hiragana.jp/)
KEGG ORTHOLOGY: K11541
KEGG   ORTHOLOGY: K11541
Entry
K11541                      KO                                     
Symbol
URA2
Name
carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2]
Pathway
map00220  Arginine biosynthesis
map00240  Pyrimidine metabolism
map00250  Alanine, aspartate and glutamate metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01240  Biosynthesis of cofactors
Module
M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Reaction
R00256  L-glutamine amidohydrolase
R00575  HCO3-:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)
R01395  ATP:carbamate phosphotransferase
R01397  carbamoyl-phosphate:L-aspartate carbamoyltransferase
R10948  ATP:HCO3- phosphotransferase
R10949  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    K11541  URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    K11541  URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase
   00220 Arginine biosynthesis
    K11541  URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     K11541  URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     K11541  URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase
Other DBs
GO: 0004088 0004070
Genes
SCE: YJL130C(URA2)
SEUB: DI49_2892
SPAO: SPAR_J00800
AGO: AGOS_ACR263C
ERC: Ecym_5206
KLA: KLLA0_E15357g
KMX: KLMA_60037(URA2)
LTH: KLTH0F05874g
VPO: Kpol_448p15
ZRO: ZYRO0D03300g
CGR: 2890801(GVI51_L05555)
NCS: NCAS_0A09770(NCAS0A09770)
NDI: NDAI_0G06170(NDAI0G06170)
TPF: TPHA_0B03110(TPHA0B03110)
TBL: TBLA_0B07830(TBLA0B07830)
TGB: HG536_0F01080
TDL: TDEL_0H01050(TDEL0H01050)
KAF: KAFR_0F02010(KAFR0F02010)
KNG: KNAG_0C02690(KNAG0C02690)
ZMK: HG535_0C00940
DHA: DEHA2A10384g
PIC: PICST_90563(URA2)
PGU: PGUG_01980
SPAA: SPAPADRAFT_49095
LEL: PVL30_002943(URA2)
CAL: CAALFM_CR07050CA(URA2)
CTP: CTRG_03135
COT: CORT_0D03260
CDU: CD36_32590
CTEN: 18246155(URA2)
YLI: 2912535(YALI2_E01571g)
CLU: CLUG_04779
CLUS: A9F13_11g00132
CAUR: CJI96_0002752
SLB: AWJ20_2038(URA2)
PPA: PAS_chr2-2_0142
PKZ: C5L36_0C03730
BNN: FOA43_002511(URA2)
BBRX: BRETT_000063(URA2)
OPA: HPODL_00057
SLUD: SCDLUD_002630
NCR: NCU08287(pyr-3)
NTE: NEUTE1DRAFT128592(NEUTE1DRAFT_128592)
SMP: 10807550(SMAC4_00930)
PAN: PODANSg7147
PBEL: QC761_606090(URA2)
PPSD: QC762_606090(URA2)
PPSP: QC763_606090(URA2)
PPSA: QC764_606090(URA2)
TTT: THITE_2115457
MTM: MYCTH_2299023
CTHR: CTHT_0032600
MGR: MGG_01537
PPEI: PpBr36_01052
PGRI: PgNI_03967
TMN: UCRPA7_7878
SSCK: SPSK_00652
FGR: FGSG_09638
FPU: FPSE_05918
FPOA: FPOAC1_012011
FVN: FVRRES_13081
FVR: FVEG_04203
FOX: FOXG_06351
NHE: NECHADRAFT_103501
FFC: NCS54_00281200
FKR: NCS57_00277200
FMU: J7337_004201
TRE: TRIREDRAFT_55928
TRR: M419DRAFT_5640
TATV: 25779744(TrAtP1_001361)
MAW: 19250694(URA2_1)
MAJ: MAA_06517
MBRN: 26237626(pyrABCN)
PCHM: VFPPC_09022
CMT: CCM_04128
AMUS: LMH87_006695
PLJ: 28882983(PLICBS_001001)
PTKZ: JDV02_007809(URA2)
VAL: VDBG_00866
VDA: VDAG_00477
CFJ: CFIO01_12029
CLUP: CLUP02_17471
CHIG: CH63R_07786
SAPO: SAPIO_CDS7513
ELA: UCREL1_6069
PFY: PFICI_05144
SSL: SS1G_08553
BFU: BCIN_12g04860
MBE: MBM_04336
PSCO: LY89DRAFT_790580
GLZ: GLAREA_10907
ANI: ANIA_00565
AFM: AFUA_6G11310
ACT: ACLA_084980
NFI: NFIA_057010
AOR: AO090023000483
ANG: An08g07420
AFV: AFLA_006827
ALUC: AKAW2_30351S
ACHE: ACHE_60114A
APUU: APUU_11522S
PCS: N7525_006351
PDP: PDIP_39750
POU: POX_d04845
TMF: EYB26_008391
TRG: TRUGW13939_00157
CIM: CIMG_09796
CPW: CPC735_022860
URE: UREG_04713
PBL: PAAG_05242
PBN: PADG_05071
ABE: ARB_01717
TVE: TRV_03411
AJE: HCAG_08357
BGH: BDBG_01634
PNO: SNOG_08506
PTE: PTT_17704
PTRR: 6347189(PtrM4_033780)
BZE: COCCADRAFT_8075
BSC: COCSADRAFT_78202
BOR: COCMIDRAFT_728
AALT: CC77DRAFT_989762
ZTR: MYCGRDRAFT_110798
PFJ: MYCFIDRAFT_86968
CBET: CB0940_06934
BCOM: BAUCODRAFT_152247
NPA: UCRNP2_6662
TML: GSTUM_00005367001
SPO: 2541544(ura1)
SOM: SOMG_01656(ura1)
CNE: CNA06000
CNB: CNBA5810
CNG: CNAG_07373
CGI: CGB_A6470C
CDEU: CNBG_9118
CDEP: 91089208(L203_104999)
TMS: TREMEDRAFT_72254
CCAC: CcaHIS019_0212810(URA2)
TVS: TRAVEDRAFT_155672
DSQ: DICSQDRAFT_87297
PCO: PHACADRAFT_103993
SHS: STEHIDRAFT_169813
HIR: HETIRDRAFT_53393
PSQ: PUNSTDRAFT_90646
ADL: AURDEDRAFT_107770
FME: FOMMEDRAFT_169884
GTR: GLOTRDRAFT_63880
RSX: RhiXN_07705
LBC: LACBIDRAFT_294748
CCI: CC1G_04764
ABP: AGABI1DRAFT122679(AGABI1DRAFT_122679)
ABV: AGABI2DRAFT188488(AGABI2DRAFT_188488)
PCUB: JR316_0012332
MRR: Moror_3989
MORE: E1B28_012198
SCM: SCHCO_02629622(SCHCODRAFT_02629622)
CPUT: CONPUDRAFT_109182
SLA: SERLADRAFT_362361
WSE: WALSEDRAFT_31765
WIC: J056_002512
UMA: UMAG_15005
PFP: PFL1_02607
SGRA: EX895_006517
MGL: MGL_1489
MRT: MRET_3870
MSYM: MSY001_2403
PGR: PGTG_15132
PTRC: PtA15_6A721
PSTR: Pst134EA_002821
MLR: MELLADRAFT_45459
BBIG: BBBOND_0311560
 » show all
Reference
PMID:2570735
  Authors
Souciet JL, Nagy M, Le Gouar M, Lacroute F, Potier S
  Title
Organization of the yeast URA2 gene: identification of a defective dihydroorotase-like domain in the multifunctional carbamoylphosphate synthetase-aspartate transcarbamylase complex.
  Journal
Gene 79:59-70 (1989)
DOI:10.1016/0378-1119(89)90092-9
  Sequence
[sce:YJL130C]
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