Entry |
|
Name |
HSV US3 to TLR2/4-NFKB signaling pathway
|
Definition |
US3 -| (TRAF6+TAK1+TAB2) |
Expanded |
K19439 -| (7189+6885+23118) |
Class |
|
Type |
Pathogen
|
Pathway |
hsa05168 | Herpes simplex virus 1 infection |
|
Disease |
H00365 | Herpes simplex virus infection |
|
Gene |
7189 | TRAF6; TNF receptor associated factor 6 |
6885 | MAP3K7; mitogen-activated protein kinase kinase kinase 7 |
23118 | TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2 |
|
Perturbant |
K19439 (US3) | US3; Simplexvirus serine/threonine-protein kinase US3 |
|
Reference |
|
Authors |
Su C, Zhan G, Zheng C |
Title |
Evasion of host antiviral innate immunity by HSV-1, an update. |
Journal |
|
Reference |
|
Authors |
Sen J, Liu X, Roller R, Knipe DM |
Title |
Herpes simplex virus US3 tegument protein inhibits Toll-like receptor 2 signaling at or before TRAF6 ubiquitination. |
Journal |
|
LinkDB |
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