Entry |
|
Name |
IAV NS1 to IFN signaling pathway
|
Definition |
NS1 -> SOCS3 -| (STAT1+STAT2+IRF9) |
Expanded |
K19396 -> 9021 -| (6772+6773+10379) |
Class |
|
Type |
Pathogen
|
Pathway |
|
Disease |
|
Gene |
9021 | SOCS3; suppressor of cytokine signaling 3 |
6772 | STAT1; signal transducer and activator of transcription 1 |
6773 | STAT2; signal transducer and activator of transcription 2 |
10379 | IRF9; interferon regulatory factor 9 |
|
Perturbant |
K19396 (NS1) | NS1; Influenza A virus non-structural protein 1 |
|
Reference |
|
Authors |
Zheng J, Yang P, Tang Y, Pan Z, Zhao D |
Title |
Respiratory Syncytial Virus Nonstructural Proteins Upregulate SOCS1 and SOCS3 in the Different Manner from Endogenous IFN Signaling. |
Journal |
|
Reference |
|
Authors |
Nan Y, Wu C, Zhang YJ |
Title |
Interplay between Janus Kinase/Signal Transducer and Activator of Transcription Signaling Activated by Type I Interferons and Viral Antagonism. |
Journal |
|
Reference |
|
Authors |
Jia D, Rahbar R, Chan RW, Lee SM, Chan MC, Wang BX, Baker DP, Sun B, Peiris JS, Nicholls JM, Fish EN |
Title |
Influenza virus non-structural protein 1 (NS1) disrupts interferon signaling. |
Journal |
|
Reference |
|
Authors |
Hale BG, Albrecht RA, Garcia-Sastre A |
Title |
Innate immune evasion strategies of influenza viruses. |
Journal |
|
LinkDB |
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