(Translated by https://www.hiragana.jp/)
KEGG NETWORK: N01576
KEGG   NETWORK: N01576
Entry
N01576                      Network                                
Name
STRAD/STK11- TSC signaling pathway
Definition
(STRADA/B+STK11) -> PRKAA1/2 -> (TSC1/2+TBC1D7)
  Expanded
(92335+55437+6794) -> (5562+5563) -> (7248+7249+51256)
Class
nt06522 mTOR signaling
Type
Reference
Pathway
hsa04150  mTOR signaling pathway
Gene
92335  STRADA; STE20 related adaptor alpha
55437  STRADB; STE20 related adaptor beta
6794  STK11; serine/threonine kinase 11
5562  PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563  PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
7248  TSC1; TSC complex subunit 1
7249  TSC2; TSC complex subunit 2
51256  TBC1D7; TBC1 domain family member 7
Reference
  Authors
Alessi DR, Sakamoto K, Bayascas JR
  Title
LKB1-dependent signaling pathways.
  Journal
Annu Rev Biochem 75:137-63 (2006)
DOI:10.1146/annurev.biochem.75.103004.142702
Reference
  Authors
Zhou W, Marcus AI, Vertino PM
  Title
Dysregulation of mTOR activity through LKB1 inactivation.
  Journal
Chin J Cancer 32:427-33 (2013)
DOI:10.5732/cjc.013.10086
Reference
  Authors
Osborne LR
  Title
Caveat mTOR: aberrant signaling disrupts corticogenesis.
  Journal
J Clin Invest 120:1392-5 (2010)
DOI:10.1172/JCI43030
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