(Translated by
https://www.hiragana.jp/
)
KEGG T01007: 488808
Canis lupus familiaris (dog): 488808
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Entry
488808 CDS
T01007
Symbol
FGFR3
Name
(RefSeq) fibroblast growth factor receptor 3 isoform X1
KO
K05094
fibroblast growth factor receptor 3 [EC:
2.7.10.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01521
EGFR tyrosine kinase inhibitor resistance
cfa04010
MAPK signaling pathway
cfa04014
Ras signaling pathway
cfa04015
Rap1 signaling pathway
cfa04020
Calcium signaling pathway
cfa04144
Endocytosis
cfa04151
PI3K-Akt signaling pathway
cfa04550
Signaling pathways regulating pluripotency of stem cells
cfa04810
Regulation of actin cytoskeleton
cfa05200
Pathways in cancer
cfa05206
MicroRNAs in cancer
cfa05219
Bladder cancer
cfa05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
488808 (FGFR3)
04014 Ras signaling pathway
488808 (FGFR3)
04015 Rap1 signaling pathway
488808 (FGFR3)
04020 Calcium signaling pathway
488808 (FGFR3)
04151 PI3K-Akt signaling pathway
488808 (FGFR3)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
488808 (FGFR3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
488808 (FGFR3)
09142 Cell motility
04810 Regulation of actin cytoskeleton
488808 (FGFR3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
488808 (FGFR3)
05206 MicroRNAs in cancer
488808 (FGFR3)
05230 Central carbon metabolism in cancer
488808 (FGFR3)
09162 Cancer: specific types
05219 Bladder cancer
488808 (FGFR3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
488808 (FGFR3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
488808 (FGFR3)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
cfa04090
]
488808 (FGFR3)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
488808 (FGFR3)
Protein kinases [BR:
cfa01001
]
Receptor tyrosine kinases (RTK)
FGFR family [OT]
488808 (FGFR3)
CD molecules [BR:
cfa04090
]
Proteins
488808 (FGFR3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
I-set
Ig_3
ig
Ig_2
V-set
FGFR3_TM
Ig_5
C2-set_2
ABC1
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
488808
NCBI-ProteinID:
XP_038334819
Ensembl:
ENSCAFG00000014993
VGNC:
40860
LinkDB
All DBs
Position
3:complement(64826871..64841704)
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AA seq
807 aa
AA seq
DB search
MGAPARALALCVAVAVVTGAASGPPGMEQRVVRRAAETPGPEPGQQEPLVFGSGDTVELT
CPSPIDSPTGPSIWVKDGVGLVPSDRILVGPRRLQVLNASHEDAGTYSCRQRLTQRILCH
FSVRVTDAPSSGDDEDGEDEAEDTAGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPT
PSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTL
DVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGT
PYVTVLKSWISESVEADARLRLANVSERDGGEYLCRASNFIGVAEKAFWLRVHGPQAAEE
ELVEAGEAGSVYAGVLSYGVGFLLFILVVAAVTLCRLRTPPKKGLGSPTVHKVSRFPLKR
QVTVSLESNSSMNSNTPLVRIARLSSGEGPALANVSELELPADPKWELSRARLTLGKPLG
EGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGRHKNII
NLLGACTQGGPLYVLVEYAAKGNLREYLRARRPPGMDYSFDTCKLPEEQLTCKDLVSCAY
QVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVK
WMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANC
THDLYMIMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFEQYSPGGQDTPS
SSSSGDDSVFAHDLLPPAPPGGGGPRT
NT seq
2424 nt
NT seq
+upstream
nt +downstream
nt
atgggcgccccggctcgcgccctcgcgctctgcgtggcggtggcggtcgtgaccggagcc
gcctcggggcccccaggcatggagcagcgcgtcgtgcggagagccgcagagaccccggga
cctgagcctggccagcaggagccactggtctttggcagcggggacactgtggagctgacc
tgcccctcacctatagacagtcccacagggcccagcatctgggtcaaggatggtgtgggg
ctggtgccctcagaccgcatcctggtggggcctcggcggctgcaggtactcaatgcctcc
catgaggatgctgggacctacagctgccggcagcggctcacccagcgcatcctgtgccat
ttcagcgtgcgtgtgacagatgctccatcctctggagatgacgaagacggggaggatgag
gctgaggacacagcaggggctccgtactggacacggcctgagcggatggacaagaagctg
ctggctgtgccggccgccaacactgtgcgcttccgctgcccggccgctggcaaccccacg
ccgtccatctcgtggctgaagaacggcaaggagttccgaggcgagcatcgcattggtggc
atcaagctgcgacatcagcagtggagcctggtcatggagagcgtggtgccctcggaccgt
gggaactacacatgcgttgtggagaacaagtttggcagcatccggcagacgtacactctg
gacgtgctggagcgctccccgcaccggcccatcctgcaggccgggctgccggccaaccag
acggccgtgctgggcagtgatgtggagttccactgcaaggtgtacagcgacgcccagccc
cacatccagtggctcaagcatgtggaggtgaacggcagcaaagtggggcccgacggtacg
ccctacgtcactgtgctcaagtcctggatcagtgagagtgtggaggccgacgcacgcctc
cgcctggccaatgtgtccgagcgtgacgggggcgagtacctctgtcgagcctccaatttc
ataggcgtggctgagaaggccttttggctgcgtgttcacgggccccaagcagccgaggag
gagctggtggaggctggtgaggctggcagcgtgtacgcaggtgtcctcagctacggggtg
ggcttcctcctcttcatcctggtggtggcagctgtgacactgtgccgtctgcgcactccc
ccgaagaagggcctgggctcgcctaccgtgcacaaggtctcccgctttccactcaagcga
caggtaacagtgtccttggagtccaactcgtccatgaactctaacacgccactggtgcgt
atcgcccggctgtcttctggggagggccctgcactggccaacgtctctgagctggagctg
cctgctgaccccaagtgggagctgtccagggcccggctgaccctaggcaagcctcttggg
gaaggctgctttggccaggtggtcatggcagaggccatcggtattgacaaggaccgggct
gccaagcctgtcactgtggctgtgaagatgctaaaagatgatgccacggacaaggacctc
tcagacctggtgtctgagatggagatgatgaagatgatcggcaggcacaagaacatcatc
aatcttctgggagcctgcacccagggtggacccctgtacgtgctggtggagtatgcagcc
aagggcaacctgcgggaatacctgcgggcaaggaggcccccgggcatggactactccttc
gacacctgcaagctgcctgaggagcagctcacctgcaaggacctggtgtcctgtgcctat
caggtggcacggggcatggagtacctggcttcccagaagtgcatccacagggacctggca
gcccgtaacgtgctggtgaccgaggacaatgtgatgaagattgcagacttcggcctggct
cgggacgtgcacaacctcgactattacaagaagaccaccaacggccggctgcctgtgaag
tggatggcacccgaggccctgtttgaccgagtctacacccaccagagtgatgtctggtcc
tttggggtgctgctctgggagatctttaccctggggggctccccataccctggcatccca
gtggaggagctcttcaagctgctgaaggagggccaccgcatggacaagccagccaactgc
acacacgacctgtacatgatcatgcgggagtgctggcatgccgtgccttcccagaggccc
acgttcaagcagctagtggaggatctggaccgcatcctcactgtgacgtccactgatgag
tatctggacctgtcggtgccttttgagcagtactcaccaggcggccaggacactcccagc
tccagctcctcgggggatgattccgtgtttgcccatgacctgctgcctccagccccaccc
ggcggtgggggtcctcggacgtga
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