(Translated by https://www.hiragana.jp/)
KEGG DRUG: ラモトリギン
KEGG   DRUG: ラモトリギン
エントリ  
D00354                      Drug                                   
一般いっぱん名めい   
ラモトリギン (JAN);
Lamotrigine (JAN/USP/INN)
商品しょうひん名めい   
ラミクタール (グラクソ・スミスクライン), ラモトリギン (共和きょうわ薬品やくひん工業こうぎょう), ラモトリギン (日医にちい工こう), ラモトリギン (日本にっぽんジェネリック), ラモトリギン (東和薬品とうわやくひん), ラモトリギン (沢井製薬さわいせいやく)
米国べいこくの商品しょうひん 
LAMICTAL (GlaxoSmithKline LLC), LAMICTAL (GlaxoSmithKline LLC)
  後発こうはつ品ひん
LAMOTRIGINE (A-S Medication Solutions), LAMOTRIGINE (A-S Medication Solutions), LAMOTRIGINE (A-S Medication Solutions), LAMOTRIGINE (A-S Medication Solutions), LAMOTRIGINE (A-S Medication Solutions), LAMOTRIGINE (Actavis Pharma), LAMOTRIGINE (Advagen Pharma Limited), LAMOTRIGINE (Advanced Rx Pharmacy of Tennessee), LAMOTRIGINE (Ajanta Pharma USA), LAMOTRIGINE (Alembic Pharmaceuticals Limited), LAMOTRIGINE (Alembic Pharmaceuticals Limited), LAMOTRIGINE (Alembic Pharmaceuticals), LAMOTRIGINE (Alembic Pharmaceuticals), LAMOTRIGINE (American Health Packaging), LAMOTRIGINE (American Health Packaging), LAMOTRIGINE (Amneal Pharmaceuticals LLC), LAMOTRIGINE (Amneal Pharmaceuticals of New York LLC), LAMOTRIGINE (Amring Pharmaceuticals), LAMOTRIGINE (Ascend Laboratories), LAMOTRIGINE (Asclemed USA), LAMOTRIGINE (Aurobindo Pharma Limited), LAMOTRIGINE (Aurobindo Pharma Limited), LAMOTRIGINE (AvKARE), LAMOTRIGINE (AvKARE), LAMOTRIGINE (Bryant Ranch Prepack), LAMOTRIGINE (Bryant Ranch Prepack), LAMOTRIGINE (Bryant Ranch Prepack), LAMOTRIGINE (Bryant Ranch Prepack), LAMOTRIGINE (Bryant Ranch Prepack), LAMOTRIGINE (Bryant Ranch Prepack), LAMOTRIGINE (Bryant Ranch Prepack), LAMOTRIGINE (Bryant Ranch Prepack), LAMOTRIGINE (Bryant Ranch Prepack), LAMOTRIGINE (Camber Pharmaceuticals), LAMOTRIGINE (Cardinal Health 107), LAMOTRIGINE (Cardinal Health 107), LAMOTRIGINE (Cipla USA), LAMOTRIGINE (DIRECT RX), LAMOTRIGINE (DirectRX), LAMOTRIGINE (Dr. Reddy's Laboratories), LAMOTRIGINE (Dr.Reddy's Laboratories Limited), LAMOTRIGINE (Dr.Reddy's Laboratories Limited), LAMOTRIGINE (Dr.Reddy's Laboratories Limited), LAMOTRIGINE (Glenmark Pharmaceuticals), LAMOTRIGINE (JUBILANT CADISTA PHARMACEUTICALS), LAMOTRIGINE (Lake Erie Medical DBA Quality Care Products LLC), LAMOTRIGINE (Lake Erie Medical DBA Quality Care Products LLC), LAMOTRIGINE (Major Pharmaceuticals), LAMOTRIGINE (NCS HealthCare of KY), LAMOTRIGINE (NorthStar Rx LLC), LAMOTRIGINE (NorthStar Rx LLC), LAMOTRIGINE (Northstar Rx LLC.), LAMOTRIGINE (Northwind Pharmaceuticals), LAMOTRIGINE (Northwind Pharmaceuticals), LAMOTRIGINE (Northwind Pharmaceuticals), LAMOTRIGINE (NuCare Pharmaceuticals), LAMOTRIGINE (NuCare Pharmaceuticals), LAMOTRIGINE (NuCare Pharmaceuticals), LAMOTRIGINE (NuCare Pharmaceuticals), LAMOTRIGINE (NuCare Pharmaceuticals), LAMOTRIGINE (NuCare Pharmaceuticals), LAMOTRIGINE (NuCare Pharmaceuticals), LAMOTRIGINE (OWP Pharmaceuticals), LAMOTRIGINE (PD-Rx Pharmaceuticals), LAMOTRIGINE (PD-Rx Pharmaceuticals), LAMOTRIGINE (PD-Rx Pharmaceuticals), LAMOTRIGINE (Par Pharmaceutical), LAMOTRIGINE (Preferred Pharmaceuticals), LAMOTRIGINE (Preferred Pharmaceuticals), LAMOTRIGINE (Preferred Pharmaceuticals), LAMOTRIGINE (Preferred Pharmaceuticals), LAMOTRIGINE (Preferred Pharmaceuticals), LAMOTRIGINE (Preferred Pharmaceuticals), LAMOTRIGINE (Preferred Pharmaeuticals), LAMOTRIGINE (Proficient Rx LP), LAMOTRIGINE (Proficient Rx LP), LAMOTRIGINE (Proficient Rx LP), LAMOTRIGINE (Proficient Rx LP), LAMOTRIGINE (Proficient Rx LP), LAMOTRIGINE (Proficient Rx LP), LAMOTRIGINE (Quallent Pharmaceuticals Health LLC), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (REMEDYREPACK), LAMOTRIGINE (RPK Pharmaceuticals), LAMOTRIGINE (RPK Pharmaceuticals), LAMOTRIGINE (RPK Pharmaceuticals), LAMOTRIGINE (Rising Pharma Holdings), LAMOTRIGINE (ST. MARY'S MEDICAL PARK PHARMACY), LAMOTRIGINE (ScieGen Pharmaceuticals), LAMOTRIGINE (Taro Pharmaceuticals U.S.A.), LAMOTRIGINE (Torrent Pharmaceuticals Limited), LAMOTRIGINE (Torrent Pharmaceuticals Limited), LAMOTRIGINE (Unichem Pharmaceuticals (USA)), LAMOTRIGINE (Zydus Lifesciences Limited), LAMOTRIGINE (Zydus Lifesciences Limited), LAMOTRIGINE (Zydus Pharmaceuticals USA), LAMOTRIGINE (Zydus Pharmaceuticals USA), LAMOTRIGINE ER (Direct_Rx), LAMOTRIGINE ER (Direct_rx), LAMOTRIGINE EXTENDED RELEASE (Par Pharmaceutical), SUBVENITE (OWP Pharmaceuticals)
組成そせい式しき   
C9H7Cl2N5
質量しつりょう    
255.0079
分子ぶんし量りょう   
256.09
構造こうぞう式しき   
クラス   
精神せいしん神経しんけい系けい用よう薬やく
 DG03199  抗こうてんかん薬やく
代謝たいしゃ酵素こうそ基質きしつ薬やく
 DG02924  UGT基質きしつ薬やく
  DG03182  UGT1A4基質きしつ薬やく
コード   
薬効やっこう分類ぶんるい: 1139 1179
ATCコード: N03AX09
商品しょうひん: D00354<JP/US>
効能こうのう    
双極そうきょく性せい障害しょうがい治療ちりょう薬やく, 抗こうけいれん薬やく, 抗こうてんかん薬やく
  疾患しっかん
Lennox-Gastaut症候群しょうこうぐん [DS:H01813]
双極そうきょく性せい障害しょうがいにおける気分きぶんエピソードの再発さいはつ・再燃さいねん抑制よくせい [DS:H01653]
ターゲット 
SCN1A [HSA:6323] [KO:K04833]
SCN2A [HSA:6326] [KO:K04834]
SCN3A [HSA:6328] [KO:K04836]
SCN4A [HSA:6329] [KO:K04837]
SCN5A [HSA:6331] [KO:K04838]
SCN8A [HSA:6334] [KO:K04840]
SCN9A [HSA:6335] [KO:K04841]
SCN10A [HSA:6336] [KO:K04842]
SCN11A [HSA:11280] [KO:K04843]
  パスウェイ
hsa04728  ドーパミン作動さどう性せいシナプス
代謝たいしゃ    
Enzyme: UGT1A4 [HSA:54657]
相互そうご作用さよう  

構造こうぞうマップ 
map07033  抗こう痙攣けいれん薬やく
map07231  ナトリウムチャネル遮断しゃだん薬やく
階層かいそう分類ぶんるい  
医療いりょう用よう医薬品いやくひんの薬効やっこう分類ぶんるい [BR:jp08301]
 1  神経しんけい系けい及および感覚かんかく器官きかん用よう医薬品いやくひん
  11  中枢ちゅうすう神経しんけい系けい用よう薬やく
   113  抗こうてんかん剤ざい
    1139  その他たの抗こうてんかん剤ざい
     D00354  ラモトリギン (JAN)
   117  精神せいしん神経しんけい用よう剤ざい
    1179  その他たの精神せいしん神経しんけい用よう剤ざい
     D00354  ラモトリギン (JAN)
医療いりょう用よう医薬品いやくひんのATC分類ぶんるい [BR:jp08303]
 N 神経しんけい系けい
  N03 抗こうてんかん薬やく
   N03A 抗こうてんかん薬やく
    N03AX その他たの抗こうてんかん薬やく
     N03AX09 ラモトリギン
      D00354  ラモトリギン (JAN) <JP/US>
医療いりょう用よう医薬品いやくひんのUSP分類ぶんるい [BR:jp08302]
 抗こうけいれん薬やく
  抗こうけいれん薬やく, その他た
   ラモトリギン
    D00354  ラモトリギン (JAN)
 双極そうきょく性せい障害しょうがい治療ちりょう薬やく
  気分きぶん安定あんてい薬やく
   ラモトリギン
    D00354  ラモトリギン (JAN)
医薬品いやくひんグループ [BR:jp08330]
 精神せいしん神経しんけい系けい用よう薬やく
  DG03199  抗こうてんかん薬やく
   D00354  ラモトリギン
 代謝たいしゃ酵素こうそ基質きしつ薬やく
  DG02924  UGT基質きしつ薬やく
   DG03182  UGT1A4基質きしつ薬やく
    D00354  ラモトリギン
医薬品いやくひんクラス [BR:jp08332]
 精神せいしん神経しんけい系けい用よう薬やく
  DG03199  抗こうてんかん薬やく [商品しょうひん一覧いちらん]
   D00354  ラモトリギン
ターゲットに基もとづく医薬品いやくひん分類ぶんるい [BR:jp08310]
 イオンチャネル
  電位でんい依存いぞん性せいイオンチャネル
   ナトリウムチャネル
    SCN1A
     D00354  ラモトリギン (JAN) <JP/US>
    SCN2A
     D00354  ラモトリギン (JAN) <JP/US>
    SCN3A
     D00354  ラモトリギン (JAN) <JP/US>
    SCN4A
     D00354  ラモトリギン (JAN) <JP/US>
    SCN5A
     D00354  ラモトリギン (JAN) <JP/US>
    SCN8A
     D00354  ラモトリギン (JAN) <JP/US>
    SCN9A
     D00354  ラモトリギン (JAN) <JP/US>
    SCN10A
     D00354  ラモトリギン (JAN) <JP/US>
    SCN11A
     D00354  ラモトリギン (JAN) <JP/US>
日本にっぽんの新薬しんやく [jp08318.html]
 新しん有効ゆうこう成分せいぶん含有がんゆう医薬品いやくひん
  D00354
薬物やくぶつ代謝たいしゃ酵素こうそとトランスポーター [jp08309.html]
 薬物やくぶつ代謝たいしゃ酵素こうそ
  D00354
リンク   
CAS: 84057-84-1
PubChem: 7847420
ChEBI: 6367
PDB-CCD: IYJ[PDBj]
LigandBox: D00354
日にち化か辞じ: J25.814H
LinkDB    

» English version   » Back

DBGET integrated database retrieval system