(Translated by
https://www.hiragana.jp/
)
KEGG T02812: 101711651
Heterocephalus glaber (naked mole-rat): 101711651
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Entry
101711651 CDS
T02812
Symbol
Fgfr3
Name
(RefSeq) fibroblast growth factor receptor 3
KO
K05094
fibroblast growth factor receptor 3 [EC:
2.7.10.1
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl01521
EGFR tyrosine kinase inhibitor resistance
hgl04010
MAPK signaling pathway
hgl04014
Ras signaling pathway
hgl04015
Rap1 signaling pathway
hgl04020
Calcium signaling pathway
hgl04144
Endocytosis
hgl04151
PI3K-Akt signaling pathway
hgl04550
Signaling pathways regulating pluripotency of stem cells
hgl04810
Regulation of actin cytoskeleton
hgl05200
Pathways in cancer
hgl05206
MicroRNAs in cancer
hgl05219
Bladder cancer
hgl05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101711651 (Fgfr3)
04014 Ras signaling pathway
101711651 (Fgfr3)
04015 Rap1 signaling pathway
101711651 (Fgfr3)
04020 Calcium signaling pathway
101711651 (Fgfr3)
04151 PI3K-Akt signaling pathway
101711651 (Fgfr3)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101711651 (Fgfr3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
101711651 (Fgfr3)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101711651 (Fgfr3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101711651 (Fgfr3)
05206 MicroRNAs in cancer
101711651 (Fgfr3)
05230 Central carbon metabolism in cancer
101711651 (Fgfr3)
09162 Cancer: specific types
05219 Bladder cancer
101711651 (Fgfr3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101711651 (Fgfr3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101711651 (Fgfr3)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hgl04090
]
101711651 (Fgfr3)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101711651 (Fgfr3)
Protein kinases [BR:
hgl01001
]
Receptor tyrosine kinases (RTK)
FGFR family [OT]
101711651 (Fgfr3)
CD molecules [BR:
hgl04090
]
Proteins
101711651 (Fgfr3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
I-set
Ig_3
ig
Ig_2
V-set
FGFR3_TM
C2-set_2
ABC1
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
101711651
NCBI-ProteinID:
XP_012928499
LinkDB
All DBs
Position
Un
AA seq
680 aa
AA seq
DB search
MTDAPSSGDDEDGEDMAEDTAGAPYWTRPERMDKKLLAVPAANTVRFRCAAAGNPMPSIS
WLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIQQTYTLDVLE
RSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVT
VLKTAGANTTDKELEVLSLRNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELAEAD
TAGSVYAGILSYGVVGFFLIILVVAAVTLCRLRSPPKKGLGSPTVHKVSRFPLKRQQVSL
ESNSSMNSNTPLVRIARLSSGEGPVLANVSELELPADPKWELSRSRLTLGKPLGEGCFGQ
VVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGAC
TQGGPLYVLVEYAAKGNLREYLRARRPPGLDYSFNTCKLPEEQLTFKDLVSCAYQVARGM
EYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEA
LFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTQDLYM
IMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFEQYSPGGQDTPSSSSSGD
DSVFTHDLLPPAPPGGGPRT
NT seq
2043 nt
NT seq
+upstream
nt +downstream
nt
atgacagatgccccctcttcaggagatgatgaagacggggaagacatggctgaagacaca
gcaggggccccatactggactcggcctgagcggatggacaagaagctgctagccgtgccg
gccgccaacactgtgcgcttccgctgcgcggctgccggcaaccccatgccctccatctcc
tggctgaagaatggcaaggaattccgtggggagcatcgcattgggggcatcaagctgcgg
caccagcagtggagcctggtcatggagagcgtggtgccttcggaccgtggcaactacacg
tgtgtggtggagaacaagttcggcagcatccagcagacatacacgctggatgtgctggag
cgctctccgcaccggcccatcctgcaggcggggctgccggccaaccagacagcagtgctg
ggaagcgatgtggaattccactgcaaggtgtacagcgatgcacagccgcatatccagtgg
ctgaagcacgtggaggtgaacggcagcaaggtgggccctgacggcacaccctacgtcact
gtgctcaagacggcgggcgctaacaccaccgacaaggagctagaggttctgtccttgcgc
aatgtcacctttgaggatgcgggggagtacacctgtctggcgggcaattctatcgggttt
tcccatcactctgcgtggctggtggtgctgccagcagaggaggagctggcagaggcggac
acggctggcagtgtgtatgcgggcatcctcagctacggggtggtgggcttcttcctcatc
atcctggtggtggcagctgtgacactctgccgcctacgcagcccccccaagaagggcctg
ggctctcccaccgtgcacaaagtctcccgtttcccgctcaagcgacagcaggtgtccttg
gagtccaactcgtccatgaactccaacacgccactggtccgcatcgcccggctgtcctcg
ggagagggccccgtgctggccaacgtgtccgagctcgagctgcctgccgaccccaagtgg
gagctgtcccggtcccggctgaccctgggcaagcctctcggggagggctgcttcggccag
gtggtcatggcggaggccattggcatcgacaaggaccgtgccgccaagcccgtcactgtg
gccgtgaagatgctgaaagatgatgccactgacaaggacctttcggaccttgtgtcagag
atggagatgatgaagatgatcggcaagcacaagaacatcatcaacctgctgggggcctgc
acgcagggtgggcccctgtatgtgctggtggagtacgcggccaagggaaacctgcgggag
tacctgcgggctcggcggcccccgggcctggactactccttcaacacctgcaagctgccc
gaggagcagctcaccttcaaggacctggtgtcctgcgcctaccaggtggcccggggcatg
gagtacctggcctcccagaagtgcatccacagggacctggccgcccgcaacgtgctggtg
actgaggacaacgtgatgaagatagcggactttggcctggcccgcgatgttcacaatctt
gactactataagaagaccaccaatggccggctgccagtgaagtggatggcacctgaagcc
ctgtttgaccgagtctatacccaccagagtgacgtctggtcctttggggtcctgctctgg
gagatcttcacactggggggctcgccgtaccccggcatccccgtggaggagctttttaag
ctgctgaaggagggccaccgcatggacaagccagccaactgcacgcaggacttgtacatg
atcatgagggagtgctggcacgctgtgccctcgcagaggcccaccttcaagcagctggtg
gaggacttggaccgcatcctcactgtgacatccaccgatgagtacctggacctgtcagtg
ccctttgagcagtactcgcccggcggccaggacacacccagctccagctcctcgggggac
gactctgtgttcacgcacgacctactgcccccggccccgcccggtgggggccctcggacg
tga
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