(Translated by
https://www.hiragana.jp/
)
KEGG T01001: 1557
Homo sapiens (human): 1557
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Entry
1557 CDS
T01001
Symbol
CYP2C19, CPCJ, CYP2C, CYPIIC17, CYPIIC19, P450C2C, P450IIC19
Name
(RefSeq) cytochrome P450 family 2 subfamily C member 19
KO
K17721
cytochrome P450 family 2 subfamily C19 [EC:
1.14.14.51
1.14.14.52
1.14.14.53
1.14.14.75
1.14.14.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00590
Arachidonic acid metabolism
hsa00591
Linoleic acid metabolism
hsa00982
Drug metabolism - cytochrome P450
hsa01100
Metabolic pathways
hsa04726
Serotonergic synapse
hsa05204
Chemical carcinogenesis - DNA adducts
Disease
H01171
Poor drug metabolism
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
1557 (CYP2C19)
00591 Linoleic acid metabolism
1557 (CYP2C19)
09111 Xenobiotics biodegradation and metabolism
00982 Drug metabolism - cytochrome P450
1557 (CYP2C19)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
1557 (CYP2C19)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
1557 (CYP2C19)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
hsa00199
]
1557 (CYP2C19)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.51 (S)-limonene 6-monooxygenase
1557 (CYP2C19)
1.14.14.52 (S)-limonene 7-monooxygenase
1557 (CYP2C19)
1.14.14.53 (R)-limonene 6-monooxygenase
1557 (CYP2C19)
1.14.14.75 fenbendazole monooxygenase (4'-hydroxylating)
1557 (CYP2C19)
Cytochrome P450 [BR:
hsa00199
]
Cytochrome P450, animal type
CYP2 family
1557 (CYP2C19)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
p450
Motif
Other DBs
NCBI-GeneID:
1557
NCBI-ProteinID:
NP_000760
OMIM:
124020
HGNC:
2621
Ensembl:
ENSG00000165841
UniProt:
P33261
Structure
PDB
LinkDB
All DBs
Position
10:94762681..94855547
Genome browser
AA seq
490 aa
AA seq
DB search
MDPFVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDVSKSLTNLSKI
YGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRW
KEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICS
IIFQKRFDYKDQQFLNLMEKLNENIRIVSTPWIQICNNFPTIIDYFPGTHNKLLKNLAFM
ESDILEKVKEHQESMDINNPRDFIDCFLIKMEKEKQNQQSEFTIENLVITAADLLGAGTE
TTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRGHMPYTDAVVHEVQRYID
LIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFK
KSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLDTTPVVNGFASVP
PFYQLCFIPV
NT seq
1473 nt
NT seq
+upstream
nt +downstream
nt
atggatccttttgtggtccttgtgctctgtctctcatgtttgcttctcctttcaatctgg
agacagagctctgggagaggaaaactccctcctggccccactcctctcccagtgattgga
aatatcctacagatagatattaaggatgtcagcaaatccttaaccaatctctcaaaaatc
tatggccctgtgttcactctgtattttggcctggaacgcatggtggtgctgcatggatat
gaagtggtgaaggaagccctgattgatcttggagaggagttttctggaagaggccatttc
ccactggctgaaagagctaacagaggatttggaatcgttttcagcaatggaaagagatgg
aaggagatccggcgtttctccctcatgacgctgcggaattttgggatggggaagaggagc
attgaggaccgtgttcaagaggaagcccgctgccttgtggaggagttgagaaaaaccaag
gcttcaccctgtgatcccactttcatcctgggctgtgctccctgcaatgtgatctgctcc
attattttccagaaacgtttcgattataaagatcagcaatttcttaacttgatggaaaaa
ttgaatgaaaacatcaggattgtaagcaccccctggatccagatatgcaataattttccc
actatcattgattatttcccgggaacccataacaaattacttaaaaaccttgcttttatg
gaaagtgatattttggagaaagtaaaagaacaccaagaatcgatggacatcaacaaccct
cgggactttattgattgcttcctgatcaaaatggagaaggaaaagcaaaaccaacagtct
gaattcactattgaaaacttggtaatcactgcagctgacttacttggagctgggacagag
acaacaagcacaaccctgagatatgctctccttctcctgctgaagcacccagaggtcaca
gctaaagtccaggaagagattgaacgtgtcattggcagaaaccggagcccctgcatgcag
gacaggggccacatgccctacacagatgctgtggtgcacgaggtccagagatacatcgac
ctcatccccaccagcctgccccatgcagtgacctgtgacgttaaattcagaaactacctc
attcccaagggcacaaccatattaacttccctcacttctgtgctacatgacaacaaagaa
tttcccaacccagagatgtttgaccctcgtcactttctggatgaaggtggaaattttaag
aaaagtaactacttcatgcctttctcagcaggaaaacggatttgtgtgggagagggcctg
gcccgcatggagctgtttttattcctgaccttcattttacagaactttaacctgaaatct
ctgattgacccaaaggaccttgacacaactcctgttgtcaatggatttgcttctgtcccg
cccttctatcagctgtgcttcattcctgtctga
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