KEGG T01002: 14960

Mus musculus (house mouse): 14960

Entry

14960             CDS       T01002

Symbol

H2-Aa, Aalpha, H-2Aa, H2Aa, I-Aalpha, IAalpha, Ia-1, Ia1

Name

(RefSeq) histocompatibility 2, class II antigen A, alpha

K06752

MHC class II antigen

Organism

mmu Mus musculus (house mouse)

Pathway

mmu04145

Phagosome

mmu04514

Cell adhesion molecules

mmu04612

Antigen processing and presentation

mmu04640

Hematopoietic cell lineage

mmu04658

Th1 and Th2 cell differentiation

mmu04659

Th17 cell differentiation

mmu04672

Intestinal immune network for IgA production

mmu04940

Type I diabetes mellitus

mmu05140

Leishmaniasis

mmu05145

Toxoplasmosis

mmu05150

Staphylococcus aureus infection

mmu05152

Tuberculosis

mmu05164

Influenza A

mmu05166

Human T-cell leukemia virus 1 infection

mmu05168

Herpes simplex virus 1 infection

mmu05169

Epstein-Barr virus infection

mmu05310

Asthma

mmu05320

Autoimmune thyroid disease

mmu05321

Inflammatory bowel disease

mmu05322

Systemic lupus erythematosus

mmu05323

Rheumatoid arthritis

mmu05330

Allograft rejection

mmu05332

Graft-versus-host disease

mmu05416

Viral myocarditis

Brite

KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    14960 (H2-Aa)
09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    14960 (H2-Aa)
09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    14960 (H2-Aa)
   04612 Antigen processing and presentation
    14960 (H2-Aa)
   04658 Th1 and Th2 cell differentiation
    14960 (H2-Aa)
   04659 Th17 cell differentiation
    14960 (H2-Aa)
   04672 Intestinal immune network for IgA production
    14960 (H2-Aa)
09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    14960 (H2-Aa)
   05164 Influenza A
    14960 (H2-Aa)
   05168 Herpes simplex virus 1 infection
    14960 (H2-Aa)
   05169 Epstein-Barr virus infection
    14960 (H2-Aa)
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    14960 (H2-Aa)
   05152 Tuberculosis
    14960 (H2-Aa)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    14960 (H2-Aa)
   05140 Leishmaniasis
    14960 (H2-Aa)
  09163 Immune disease
   05310 Asthma
    14960 (H2-Aa)
   05322 Systemic lupus erythematosus
    14960 (H2-Aa)
   05323 Rheumatoid arthritis
    14960 (H2-Aa)
   05320 Autoimmune thyroid disease
    14960 (H2-Aa)
   05321 Inflammatory bowel disease
    14960 (H2-Aa)
   05330 Allograft rejection
    14960 (H2-Aa)
   05332 Graft-versus-host disease
    14960 (H2-Aa)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    14960 (H2-Aa)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    14960 (H2-Aa)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    14960 (H2-Aa)
Exosome [BR:mmu04147]
Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   14960 (H2-Aa)
  Exosomal proteins of epithelial cells
   14960 (H2-Aa)
  Exosomal proteins of breast milk
   14960 (H2-Aa)

SSDB

Motif

Pfam:

MHC_II_alpha C1-set Ig_3 C2-set_2

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

MGI:

Ensembl:

UniProt:

Structure

LinkDB

Position

17:complement(34501718..34506797)

AA seq 256 aa
MPRSRALILGVLALTTMLSLCGGEDDIEADHVGTYGISVYQSPGDIGQYTFEFDGDELFY
VDLDKKETVWMLPEFGQLASFDPQGGLQNIAVVKHNLGVLTKRSNSTPATNEAPQATVFP
KSPVLLGQPNTLICFVDNIFPPVINITWLRNSKSVADGVYETSFFVNRDYSFHKLSYLTF
IPSDDDIYDCKVEHWGLEEPVLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTIFI
IQGLRSGGTSRHPGPL

NT seq 771 nt +upstreamnt +downstreamnt
atgccgcgcagcagagctctgattctgggggtcctcgccctgaccaccatgctcagcctc
tgtggaggtgaagacgacattgaggccgaccacgtaggcacctatggtataagtgtatat
cagtctcctggagacattggccagtacacatttgaatttgatggtgatgagttgttctat
gtggacttggataagaaggagactgtctggatgcttcctgagtttggccaattggcaagc
tttgacccccaaggtggactgcaaaacatagctgtagtaaaacacaacttgggagtcttg
actaagaggtcaaattccaccccagctaccaatgaggctcctcaagcgactgtgttcccc
aagtcccctgtgctgctgggtcagcccaacaccctcatctgctttgtggacaacatcttc
cctcctgtgatcaacatcacatggctcagaaatagcaagtcagtcgcagacggtgtttat
gagaccagcttcttcgtcaaccgtgactattccttccacaagctgtcttatctcaccttc
atcccttctgacgatgacatttatgactgcaaggtggaacactggggcctggaggagccg
gttctgaaacactgggaacctgagattccagcccccatgtcagagctgacagagactgtg
gtctgtgccctggggttgtctgtgggccttgtgggcatcgtggtgggcaccatcttcatc
attcaaggcctgcgatcaggtggcacctccagacacccagggcctttatga

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