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BCAS2

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BCAS2
Identifikatori
AliasiBCAS2
Vanjski ID-jeviOMIM: 605783 MGI: 1915433 HomoloGene: 4291 GeneCards: BCAS2
Lokacija gena (čovjek)
Hromosom 1 (čovjek)
Hrom.Hromosom 1 (čovjek)[1]
Hromosom 1 (čovjek)
Genomska lokacija za BCAS2
Genomska lokacija za BCAS2
Bend1p13.2Početak114,567,557 bp[1]
Kraj114,581,629 bp[1]
Lokacija gena (miš)
Hromosom 3 (miš)
Hrom.Hromosom 3 (miš)[2]
Hromosom 3 (miš)
Genomska lokacija za BCAS2
Genomska lokacija za BCAS2
Bend3|3 F2.2Početak103,078,971 bp[2]
Kraj103,086,482 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
Ćelijska komponenta Replikacijski protein A
catalytic step 2 spliceosome
spliceosomal complex
Jedarce
precatalytic spliceosome
Prp19 complex
nukleoplazma
jedro
centrosom
nuclear speck
U2-type catalytic step 2 spliceosome
Biološki proces RNA splicing, via transesterification reactions
mRNA processing
Prerada RNK
mRNA splicing, via spliceosome
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_005872

NM_026602
NM_001356330
NM_001356331

RefSeq (bjelančevina)

NP_005863

NP_080878
NP_001343259
NP_001343260

Lokacija (UCSC)Chr 1: 114.57 – 114.58 MbChr 3: 103.08 – 103.09 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Pre-iRNK-preradni faktor SPF27 jest protein koji je kod ljudi kodiran genom BCAS2 sa hromosoma 1.[5][6][7]

Amiokiselininska sekvenca

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Dužina polipeptidnog lanca je 225 aminokiselina, a molekulska težina 26.131 Da.[8]

1020304050
MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYL
SYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDI
TAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQ
KELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIV
QLENEIYQIKQQHGEANKENIRQDF

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000116752 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000005687 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Neubauer G, King A, Rappsilber J, Calvio C, Watson M, Ajuh P, Sleeman J, Lamond A, Mann M (Oct 1998). "Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex". Nat Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529. S2CID 585778.
  6. ^ Nagasaki K, Maass N, Manabe T, Hanzawa H, Tsukada T, Kikuchi K, Yamaguchi K (Aug 1999). "Identification of a novel gene, DAM1, amplified at chromosome 1p13.3-21 region in human breast cancer cell lines". Cancer Lett. 140 (1–2): 219–26. doi:10.1016/S0304-3835(99)00091-9. PMID 10403562.
  7. ^ "Entrez Gene: BCAS2 breast carcinoma amplified sequence 2".
  8. ^ "UniProt, O75934" (jezik: engleski). Pristupljeno 21. 11. 2021.

Dopunska literatura

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Vanjski linkovi

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BCAS2 detalji ljudskog genoma u UCSC Genome Browser.